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Perivascular cells could induce microglial malfunction associated with Alzheimer’s disease
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Perivascular cells could induce microglial malfunction associated with Alzheimer’s disease

by Ingrid Fadelli, Medical Xpress Representative 3D reconstructed image showing Homer1 engulfment within CD68+ lysosomes of P2Y12+ microglia. Credit: De Schepper et al Microglia are primary immune cells that safeguard the mammalian brain, partly by devouring or ‘phagocytosing’ pathogens and toxic debris. Recent genetic studies have consistently highlighted the role of microglia in the development of Alzheimer’s...