Checkerboard plot showing 18F-RO-948-positivity results (black cells: bilaterally positive; gray cells: unilaterally positive) of anterior and posterior Braak regions (19), and estimated Braak stages (right column) (20). esV = extrastriatal …more In the diagnosis of Alzheimer’s disease and the search for effective treatments, tau tangles in the brain have joined amyloid build-up as markers of...