Precise delivery of therapeutic drugs into diseased tissue remains a challenge in a variety of cases. Tumors can be hard to seed with chemo agents, particularly when the blood flow is not favorable for delivery. Now, researchers at the Max Planck Institute for Intelligent Systems in Germany have developed microscopic drug delivery devices that can...
UNIVERSITAT AUTONOMA DE BARCELONA An international study by the Institute of Neuroscience of the UAB (INC-UAB), Emory University and Hospital Universitario La Paz, published in the PNAS journal, shows that patients suffering from Lesch-Nyhan, a rare neurological disease, present biochemical alterations in skin cells (fibroblasts), urine and cerebrospinal fluid. Researchers have also discovered why these...
Psychedelics such as LSD and magic mushrooms have proven highly effective in treating depression and post-traumatic stress disorders, but medical use of these drugs is limited by the hallucinations they cause. “What if we could redesign drugs to keep their benefits while eliminating their unwanted side effects?” asks Ron Dror, an associate professor of computer...
by Leiden University The endogenous compound anandamide—often referred to as the body’s own marijuana—plays a role in erasing memories of a traumatic event. This was discovered by an international team led by Leiden chemist Mario van der Stelt. The results have been published in Nature Chemical Biology and may provide a starting point for the...
May 5, 2020 — A study just released by Columbia University Mailman School of Public Health is reporting a blood-DNA-methylation measure that is sensitive to variation in the pace of biological aging among individuals born the same year. The tool – DunedinPoAm — offers a unique measurement for intervention trials and natural experiment studies investigating...
by American Physiological Society Regular consumption of sugary soda sweetened with high-fructose corn syrup (HFCS) reduces kidney blood flow, which could be linked to a greater risk of developing chronic kidney disease (CKD), according to a recently published paper in the American Journal of Physiology-Renal Physiology. The study, chosen as an APSselect article for May,...
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES The human cell has a wide variety of receptors on its surface that many molecules and therapeutic drugs can bind to in order to activate signals inside the cell to regulate different physiological functions. GPCRs are the largest – and a very important – family of receptors...
SIAVASH PARKHIDEH CARDIOLOGY, DIAGNOSTICS, GERIATRICS, MEDICINE, SPORTS MEDICINE Researchers from University of Massachusetts at Amherst have developed a new smart pajama, dubbed Phyjama, that can track physiological signals during sleep. Their work demonstrates that the technology can reliably measure heart rate, breathing rate, and sleep position during the course of the night. One day, advances...
Posted Today Assistant professor of medical engineering Wei Gao is enriching the field of personalized and precision medicine with an abundant source of chemical data: sweat. Gao’s perspiration-analysis technology enables early detection of physiological aberrations, customized treatment plans, and greater accuracy in drug monitoring. Low energy, for example, is a symptom that could be associated with a multitude of...
Vegetarians showed greater visual memory gains than meat eaters after taking creatine AMERICAN PHYSIOLOGICAL SOCIETY Orlando, Fla. (April 8, 2019)–Vegetarians who take the dietary supplement creatine may enjoy improved brain function, according to a new study. The research will be presented today at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2019 in Orlando, Fla. Creatine is a chemical...
