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Immune cells in pituitary gland help balance hormones, researchers discover

by University of Turku Macrophages, marked in yellow, connect hormone-secreting cells (magenta) and blood vessels (gray) in the mouse pituitary gland. Scale is 10 µm. Credit: Henna Lehtonen In a new study published in Cell Reports, Finnish researchers show that pituitary macrophages, the immune cells located in the pituitary gland, help regulate hormonal balance. It is possible that in...

Purified pituitary tissue generated from stem cells
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Purified pituitary tissue generated from stem cells

by Cell Press Credit: Unsplash/CC0 Public Domain Researchers have successfully converted human pluripotent stem cells into purified pituitary cells that aggregated into hormone-secreting organoids. As reported June 8 in the journal Stem Cell Reports, transplantation of these 3D pituitaries into mice with hypopituitarism resulted in long-lasting improvement in levels of adrenocorticotropic hormone (ACTH), which is normally...