September 11, 2024 by Jennifer Michalowski, Massachusetts Institute of Technology Credit: Current Biology (2024). DOI: 10.1016/j.cub.2024.08.004 Placebos are inert treatments, generally not expected to impact biological pathways or improve a person’s physical health. But time and again, some patients report that they feel better after taking a placebo. Increasingly, doctors and scientists are recognizing that...
by Elana Gotkine For patients with moderate-to-severe plaque psoriasis, the interleukin-23-receptor antagonist peptide JNJ-77242113 shows greater efficacy than placebo, according to a study published in the Feb. 8 issue of the New England Journal of Medicine. Robert Bissonnette, M.D., from Innovaderm Research in Montreal, and colleagues conducted a phase 2 dose-finding trial involving 255 patients...
by King’s College London Neuroanatomical patterns across the dimensions. False discovery rate- (FDR-) corrected voxel-wise comparison of gray-matter volume differences in Dimension 1 (top row) and Dimension 2 (bottom row) versus controls are presented in transverse, sagittal, and coronal sections. Color bar indicates strength of group differences (MIDAS statistic) between MDD and healthy control participants. Credit:...
Eve Bender October 30, 2023 TOPLINE: Ketamine was no more effective than placebo in reducing depressive symptoms in surgical patients with major depressive disorder (MDD), results of a new study, which contradict prior research, suggest. Although symptoms improved in both study groups, investigators say participants’ expectations of an improvement from ketamine may be driving that result. METHODOLOGY: TAKEAWAY:...
It is the latest health fad – present in everything from soy lattes to vegan cakes. But there may be something in the health craze for turmeric after all. A scientifically robust study, published in a respected medical journal, has found that the yellow spice may be an effective painkiller for arthritis. A randomised, double-blinded,...
PULLMAN, Wash. – People suffering from post-traumatic distress disorder report that cannabis reduces the severity of their symptoms by more than half, at least in the short term, according to a recent study led by Carrie Cuttler, a Washington State University assistant professor of psychology. Cuttler and her colleagues analyzed data of more than 400...
by Deborah Kotz, University of Maryland School of Medicine A new landmark study by researchers at the University of Maryland School of Medicine (UMSOM) found that patients with a vascular condition, called abdominal aortic aneurysm, received no benefits from taking a common antibiotic drug to reduce inflammation. Patients who took the antibiotic doxycycline experienced no...
Several clinical trials have reported beneficial effects of organic nitrates on bone health, which could lead to a reduced risk of fractures. Some of these trials have been retracted because of scientific misconduct; however. A new study published in the Journal of Bone and Mineral Research found that organic nitrates do not have clinically relevant...
by American College of Rheumatology According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis, but did significantly reduce the progression of joint damage over placebo and seems...
(HealthDay)—With millions of pain-plagued Americans looking for an alternative to opioids, the solution for some might be no medicine at all. New research suggests that a good many back pain patients might find relief in a “dummy” sugar pill, eliminating their need for strong medication. About half the chronic back pain patients in a new...
