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Protein score, from a single plasma sample, predicts atherosclerotic cardiovascular disease
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Protein score, from a single plasma sample, predicts atherosclerotic cardiovascular disease

DECODE GENETICS IMAGE: KARI STEFANSSON CEO OF DECODE GENETICS AND AUTHOR ON THE PAPER WITH HANNES HELGASON SCIENTIST AT DECODE GENETICS AND AUTHOR ON THE PAPER. view more CREDIT: DECODE GENETICS In a large retrospective analysis using measurements of thousands of plasma proteins in primary and secondary event populations, scientists from deCODE genetics a subsidiary...

New method enables detection of plasma biomarkers cheaply and at scale
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New method enables detection of plasma biomarkers cheaply and at scale

by Nancy Fliesler, Children’s Hospital Boston Perchloric acid depletion workflow and method validation. (A) Workflow: PerCA plasma proteomic platform. (B) Principal components analysis to identify possible batch effects between phases 1 and 3 (colored in purple, pink, and brown) acquired over a 10-month period. (C) Sample-to-sample correlation of all reference plasma samples from the 44 plates....

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EARLY, HIGH DOSES OF PLASMA CAN PREVENT COVID HOSPITALIZATIONS

Three years into the COVID-19 pandemic, new variant outbreaks continue to fuel economic disruptions and hospitalizations across the globe. Effective therapies remain unavailable in much of the world, and circulating variants have rendered monoclonal antibody treatments ineffective. In the new study in Clinical Infectious Diseases, researchers analyzed clinical data and concluded that among outpatients with COVID-19, antibodies to SARS-CoV-2 given...

The largest ever study of the plasma proteome published
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The largest ever study of the plasma proteome published

by deCODE genetics  Dr. Kari Stefansson CEO of deCODE genetics and one of the senior authors on the paper. Credit: deCODE genetics In a study published today in Nature Genetics, scientists at deCODE genetics , a subsidiary of the pharmaceutical company Amgen, demonstrate how measuring the levels of a large number of proteins in plasma at...

Evidence lags behind excitement over blood plasma as a coronavirus treatment
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Evidence lags behind excitement over blood plasma as a coronavirus treatment

Researchers call for more rigorous clinical trials as rumours abound that US regulators are considering widening access to the potential therapy. Plasma is a yellow liquid left behind after cells are removed from donated blood. It contains antibodies and immune-regulating proteins that could help treat disease.Credit: Guillermo Legaria/Getty US President Donald Trump has called on...

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Seasonal flu vaccinations don’t ‘stick’ long-term in bone marrow

A study from Emory Vaccine Center provides insights into why the boost in immunity from seasonal flu vaccination lasts for months but not years, unlike some childhood vaccinations. The home base for immune cells that produce antibodies is the bone marrow. Seasonal flu vaccination does increase the number of antibody-producing cells specific for flu in...

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New research offers hope for treating Parkinson’s disease

Reviewed by James Ives, M.Psych. (Editor) The American Academy of Neurology (AAN) has published, on August 12, the results of a research project conducted jointly by Cardiocentro Ticino and the EOC Neurocentro, which delivers a message of hope in the fight against Parkinson’s disease, as well as providing encouraging news for the USI Faculty of...

Scientists develop synthetic blood-thinner that doesn’t cause bleeding side-effects
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Scientists develop synthetic blood-thinner that doesn’t cause bleeding side-effects

by Ecole Polytechnique Federale de Lausanne gulation factor XII (FXII), and the mice without the enzyme had a highly reduced risk of thrombosis without bleeding side-effects. The discovery triggered a race for FXII inhibitors. The Laboratory of Therapeutic Proteins and Peptides of Professor Christian Heinis at EPFL has now developed the first synthetic inhibitor of...

Exercise and PRP promising for shoulder pain in wheelchair users with spinal cord injury
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Exercise and PRP promising for shoulder pain in wheelchair users with spinal cord injury

A team of specialists in regenerative rehabilitation reported positive results from pilot study of the combination of a single injection of platelet-rich plasma (PRP) and a home-based exercise program, for wheelchair users with recalcitrant shoulder pain KESSLER FOUNDATION THE STUDY WAS CONDUCTED AT THE DERFNER-LIEBERMAN LABORATORY FOR REGENERATIVE REHABILITATION RESEARCH IN THE CENTER FOR SPINAL...

Neutralizing antibodies isolated from COVID-19 patients may suppress virus
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Neutralizing antibodies isolated from COVID-19 patients may suppress virus

by Columbia University Irving Medical Center Cryo-EM reconstructions show how two different antibodies (blue) bind to the spike protein of the SARS-CoV-2 virus. Credit: David Ho / Columbia University Irving Medical Center Researchers at Columbia University Irving Medical Center have isolated antibodies from several COVID-19 patients that, to date, are among the most potent in...

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