Researchers from Osaka University find that in immune tissues, plasma cells that express certain proteins are more likely to migrate to the bone marrow, where they help create long-lasting antibody responsesPeer-Reviewed Publication Osaka University FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail image: Integrin β7hi plasma cells with KLF2 preferentially egress from lymphoid tissues toward the bone marrow.view more Credit: Ise, et al. J...
Tag: <span>plasma cells</span>
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Engineered plasma cells show long-lasting antileukemic activity in mice
JULY 2, 2024 by Cell Press Acute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public Domain Researchers show for the first time that engineered human plasma B cells can be used to treat a disease—specifically leukemia—in a humanized animal model. The results mark a key step in the realization of ePCs as therapies to treat cancer, auto-immune...
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Tumor-infiltrating B cells and plasma cells influence early-stage lung cancer biology, immunotherapy responses
by University of Texas M. D. Anderson Cancer Center Credit: Pixabay/CC0 Public Domain Through extensive single-cell analysis, researchers at The University of Texas MD Anderson Cancer Center have created a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, highlighting previously unappreciated roles these immune cells play in tumor development and...