IN BRIEF Researchers have developed a method to turn skin cells into pluripotent stem cells which are then reprogrammed to become microglia cells. These brain cells play a crucial role in the development of neurological diseases, like Alzheimer’s disease. Studying them could help scientists discover new treatments. FROM SKIN TO BRAIN The brain is one...
Tag: <span>pluripotent stem (iPS) cells</span>
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Scientists reprogram embryonic stem cells to expand their potential cell fates
miR-34a-deficient embryonic stem cell culture is enriched with cells with expanded developmental potential as shown by their strong MuERV-L induction (red). These cells are distinct from the classic embryonic stem cells shown by the Oct4 staining (green). MuERV-L are the family of murine endogenous retroviruses activated in the very early embryo. Researchers from the University...