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Polycystic kidney disease: How sugar may be a factor
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Polycystic kidney disease: How sugar may be a factor

Researchers say sugar can affect cysts that may be a factor in a common type of kidney disease. Oliver Bunic/Bloomberg via Getty Images New research conducted in a laboratory setting may potentially have significant effects on the management of polycystic kidney disease (PKD), a condition impacting more than 500,000 individuals in the United States. Organoids...

UT Southwestern researchers identify a gene therapy target for polycystic kidney disease
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UT Southwestern researchers identify a gene therapy target for polycystic kidney disease

UT SOUTHWESTERN MEDICAL CENTER IMAGE: THIS IMAGE SHOWS A SEVERELY CYSTIC KIDNEY FROM A ADPKD MOUSE MODEL (LEFT). DELETING THE PKD1 MIR-17 BINDING SITE MARKEDLY REDUCES CYST GROWTH (RIGHT). YELLOW INDICATES KIDNEY COLLECTING DUCTS AND BLUE INDICATES NUCLEI. CREDIT: UT SOUTHWESTERN MEDICAL CENTER Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs...

Chemical modification of RNA could play key role in polycystic kidney disease
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Chemical modification of RNA could play key role in polycystic kidney disease

by  UT Southwestern Medical Center Credit: Pixabay/CC0 Public Domain A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the U.S., UT Southwestern researchers report in a new study. The findings, published...