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Polygenic risk scores identify high-risk individuals in European and Asian ancestry, but less so in African ancestry
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Polygenic risk scores identify high-risk individuals in European and Asian ancestry, but less so in African ancestry

by University of Helsinki Credit: Pixabay/Gerd Altmann An international research consortium led by the University of Helsinki has performed the largest study to date evaluating transferability of genome-wide polygenic risk scores across ancestries. Polygenic risk scores (PRS) measure genetic disease susceptibility by combining risk effects across the genome. The team focused on four common diseases with great...