By Dr. Surat P, Ph.D. Reviewed by Michael Greenwood, M.Sc. Enhancer RNAs, or eRNAs, are short non-coding RNA molecules that are transcribed from the loci of enhancers. They are involved in the regulation of gene transcription and can be a therapeutic target for diseases. Enhancer RNAs were discovered in 2010 through high-throughput sequencing to detect stimulus-dependent enhancers. This revealed the RNApolymerase II-dependent transcription of enhancer RNAs. These are...