by Birkbeck University of London Cryo-tomography of perforin prepores.(A) Overview of a typical cryotomogram of liposomes with attached perforin prepores. Prepore assemblies are highlighted with arrows. (B) Close-up view of prepores attached to the lipid bilayers. (C) Manual docking of soluble perforin monomer (purple, PDB code 3NSJ) into the 3D volume of a perforin prepore...
