by Saint Louis University Graphical abstract. Credit: Journal of Clinical Investigation (2022). DOI: 10.1172/JCI157738 Though chemotherapy can be lifesaving, the cancer treatment often leaves patients suffering from debilitating side effects, including cognitive impairments in processing speed, memory, executive function and attention. Dubbed “chemo brain,” these lingering symptoms can dramatically impact patients’ quality of life long after they...
Interview conducted by Emily Henderson, B.Sc.Mar 30 2022 Thought LeadersDr. Ahmed G. IbrahimAssistant Professor, Smidt Heart InstituteCedars-Sinai Medical Center In this interview, we speak to Dr. Ahmed G. Ibrahim about his latest research that has discovered a new possible treatment for COVID-19. Please could you introduce yourself and tell us what inspired your latest research into...
NIIGATA UNIVERSITY IMAGE: Immunostaining: Top panel SH-SY5Y cells transfected with GBA are stained for dsDNA (magenta), histone H2B (green), and Hsp60 (turquoise). White arrows indicate cytosolic dsDNA of mitochondrial origin. Triple siRNA: Knockdown of GBA, ATP13A2, and PINK1 expression with siRNAs. Coimmunostaining: Bottom panel In situ hybridization of mitochondrial DNA and coimmunostaining for histone H2B...
