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Potential drug for Alzheimer’s disease prevention found safe and effective in animals
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Potential drug for Alzheimer’s disease prevention found safe and effective in animals

ROCKEFELLER UNIVERSITY PRESS IMAGE: Compared with a control (left), treatment with the novel GSM (right) reduces the number of amyloid plaques (green) and proinflammatory cells called microglia (magenta) in the brains of mice carrying mutations linked to early-onset Alzheimer’s disease. CREDIT: ©2021 RYNEARSON ET AL. ORIGINALLY PUBLISHED IN JOURNAL OF EXPERIMENTAL MEDICINE. HTTPS://DOI.ORG/10.1084/JEM.20202560 Researchers at the University of...

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Texas A&M-UTMB team identifies potential drug to treat SARS-CoV-2

TEXAS A&M UNIVERSITY A federally approved heart medication shows significant effectiveness in interfering with SARS-CoV-2 entry into the human cell host, according to a new study by a research team from Texas A&M University and The University of Texas Medical Branch (UTMB). The medication bepridil, which goes by the trade name Vascor, is currently approved by the...

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Genetic information can predict predisposition to rare and common blood diseases

Studies identify bulk of genetic variation that influences blood cell traits Two large-scale genetic studies have identified the bulk of genetic variation that influences medically-important characteristics of our blood cells. Researchers from the Wellcome Sanger Institute, the Broad Institute of MIT and Harvard, and colleagues from 101 research institutions world-wide, have studied hundreds of thousands...

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Handgrip strength shown to identify people at high risk of type 2 diabetes

Findings demonstrate handgrip strength could be a cost-effective early screening tool A simple test such as the strength of your handgrip could be used as a quick, low-cost screening tool to help healthcare professionals identify patients at risk of type 2 diabetes. In new research, scientists at the universities of Bristol and Eastern Finland measured...

RethiNKing which immune cells are the best weapon against lung cancer
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RethiNKing which immune cells are the best weapon against lung cancer

WALTER AND ELIZA HALL INSTITUTE AUSTRALIAN RESEARCHERS HAVE IDENTIFIED ‘NATURAL KILLER’ CELLS AS AN IMPORTANT COMPONENT OF ANTI-TUMOUR IMMUNITY TO LUNG CANCER. IMAGE: SECTIONS OF LUNG CONTAINING TUMOURS, BY DR KAREN DOGGETT Immune cells called ‘natural killer’ (NK) cells could be a powerful weapon for fighting lung cancer, according to Australian researchers. Studying preclinical and...

Study targets gene associated with Alzheimer’s disease
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Study targets gene associated with Alzheimer’s disease

by Bob Shepard, University of Alabama at Birmingham The neurons in this image are stained blue, indicating the presence of the BIN1 protein. Points of direct interaction between BIN1 and calcium channels are in purple. Credit: University of Alabama at Birmingham Researchers at the University of Alabama at Birmingham are on the track of a...

COVID-19 and mRNA Vaccines—First Large Test for a New Approach
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COVID-19 and mRNA Vaccines—First Large Test for a New Approach

n January 10, Chinese researchers posted the novel coronavirus’ RNA sequence on a preprint server. Immediately, scientists who study genetic vaccines turned their efforts to the emerging pathogen that causes coronavirus disease 2019 (COVID-19). They knew that rapid response genetic platforms could shave precious weeks to months off development, crucial during a pandemic.\ They were...

Weak electric currents could help combat superbugs
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Weak electric currents could help combat superbugs

Scientists have shown that currents measured in millionths of an amp kill bacteria by disrupting their outer membranes. The finding may inspire new antimicrobial technologies that use electricity to slow the spread of antibiotic resistant infections. New research suggesting that electricity can kill bacteria may have long-term implications for combating ‘superbugs.’ Scientists have known since...

Dartmouth-led team engineers new treatment for drug-resistant bacterial infections
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Dartmouth-led team engineers new treatment for drug-resistant bacterial infections

THAYER SCHOOL OF ENGINEERING AT DARTMOUTH A MOLECULAR MODEL OF THE F12 BIOTHERAPY SHOWS THE FOLD OF ITS POLYPEPTIDE BACKBONE. RESIDUAL T CELL EPITOPES ARE MAPPED ONTO THE STRUCTURE AND COLORED FROM WHITE (NO EPITOPES). The Centers for Disease Control and Prevention (CDC) has prioritized finding effective treatment of Methicillin-resistant Staphylococcus aureus (MRSA), one of...

Attacking tumors from the inside
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Attacking tumors from the inside

Two experimental drugs fight non-small cell lung cancer by affecting their blood vessels, oxygen levels, and other environmental factors UT SOUTHWESTERN MEDICAL CENTER FROM LEFT: DRS. RALPH MASON, LI LIU, AND YIHANG GUO, AND RESEARCHER JENI GERBERICH USED A NEW TOOL CALLED MULTISPECTRAL OPTOACOUSTIC TOMOGRAPHY TO EXAMINE NON-SMALL CELL LUNG CANCER TUMORS GROWING. DALLAS –...