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Study identifies a new potential target for treating vascular disease
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Study identifies a new potential target for treating vascular disease

by Elsevier A new study shows that when fragile-X related protein-1 (FXR1) is absent, vascular smooth muscle cells (VSMC) proliferate more slowly, become senescent, and scar tissue (neointima) development is reduced. Therefore, drugs targeting FXR1 may treat vascular proliferative diseases. Credit: The American Journal of Pathology Vascular diseases, including myocardial infarction, stroke, renal failure, and peripheral vascular...

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Study identifies potential target for osteoporosis treatments

ELIFE Channels on the surface of bone cells called osteocytes help build stronger bones in response to mechanical stress, shows a study published today in eLife. This discovery may help scientists develop new treatments for osteoporosis or other conditions that contribute to bone loss in patients. Physical activities that exert mechanical stress on the bones...

Study discovers potential target for treating aggressive cancer cells
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Study discovers potential target for treating aggressive cancer cells

by Kerry Benson,  Brown University As researchers and medical professionals work to develop new treatments for cancer, they face a variety of challenges. One is intratumor heterogeneity—the presence of multiple kinds of cancer cells within the same tumor. Often, these “mosaic” tumors include cells, such as polyploidal giant cancer cells, that have evolved to become aggressive and resistant...