by Queen Mary, University of London Credit: CC0 Public Domain New research has identified hundreds of proteins that might contribute to the onset of common, chronic metabolic diseases such as type 2 diabetes, and consequently pathways to potential treatments. The study, published in Nature Metabolism, was led by an international research team from the Medical Research Council...
By mapping all the protein interactions of a dementia-linked protein in the brain called Tau, a team of Weill Cornell Medicine investigators has created a road map for identifying potential new treatment targets for Alzheimer’s disease and related dementia. Tau protein has long been implicated in neurodegenerative diseases. Mutations in the gene that encodes the Tau protein...
Using cryo-electron microscopy, researchers at Case Western Reserve University School of Medicine and National Institutes of Health open door to new level of detail in study of abnormal proteins that cause untreatable neurodegenerative conditions The highest-ever resolution imaging of an infectious prion has provided the first atomic-level data of how these abnormal proteins are assembled to cause...
Intervertebral discs provide load support and motion between vertebrae in the spine, but when they start to break down and compress due to aging, disease, or injury, a person experiences significant pain and reduced mobility. An interdisciplinary team of researchers at Washington University in St. Louis found a way to deliver new cells to the cushioning material...
