Scientists identify treatment target that disrupts proteins’ interaction, offering hope for new therapeutic approachPeer-Reviewed Publication CITY OF HOPE PROTEIN SURFACE (LEFT) AND RIBBON (RIGHT) MODELS OF INTEGRIN ΑV’S Β-PROPELLER DOMAIN ILLUSTRATE THE CAPACITY OF CPD_AV2 (YELLOW) IN DISRUPTING THE INTERACTION BETWEEN INTEGRIN Β5’S ΒA LOOP (CYAN; GREEN INDICATES THE KEY INTERACTING RESIDUE LYSINE 287) AND...
by Oxford University Press A new study in Nucleic Acids Research, published by Oxford University Press, suggests a possible effective treatment strategy for patients suffering from prion disease. Prion disease is a rapidly fatal and currently untreatable neurodegenerative disease. While prion disease is quite rare, it typically causes rapid neurodegeneration. About 300 cases of prion...
by Fred Hutchinson Cancer Research Center Millions of Americans live with the pain and physical limitations of arthritis and other inflammatory diseases. Steroids and other drugs can offer relief, but they can also come with a host of serious side effects. A new study published March 4 in Science Translational Medicine suggests that a scorpion-derived...
