In the watery inside of a cell, complex processes take place in tiny functional compartments called organelles. Energy-producing mitochondria are organelles, as is the frilly golgi apparatus, which helps to transport cellular materials. Both of these compartments are bound by thin membranes. But in the past few years, research at Whitehead Institute and elsewhere has...
Tag: <span>preventing cancer</span>
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Vitamin D may help prevent a common side effect of anti-cancer immunotherapy
New research indicates that taking vitamin D supplements may help prevent a potentially serious side effect of a revolutionary form of anti-cancer therapy. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS). Immune checkpoint inhibitors help the immune system recognize and combat cancer cells, and although these...
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How cancer drugs find their targets could lead to a new toolset for drug development
by Whitehead Institute for Biomedical Research The molecular structure of the cancer drug cisplatin causes it to concentrate in tiny non-membrane bound organelles called condensates held together by the protein MED1. By altering other drugs to concentrate in specific condensates, drug developers may be able to improve targeting efficacy in future. Credit: Isaac Klein, Whitehead...
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US regulators approve new type of contraceptive gel
by Linda A. Johnson Phexxi, a contraceptive made by San Diego-based Evofem Bioscience. The Food and Drug Administration on Friday, May 22, 2020 approved the new contraceptive. (Christine Blackburne via AP) U.S. regulators on Friday approved a birth control gel that works in a new way to prevent pregnancy. Phexxi—pronounced FECK’-see—comes in an applicator that...
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Long-acting injectable cabotegravir highly effective at preventing HIV infection
by University of North Carolina at Chapel Hill School of Medicine The HIV Prevention Trials Network (HPTN) announced today results from HPTN 083, a global randomized, controlled, double-blind study that compared the safety and efficacy of long-acting injectable cabotegravir (CAB LA) to daily oral tenofovir/emtricitabine (TDF/FTC) (Truvada) for pre-exposure prophylaxis (PrEP). The study showed that...
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Novel study documents marked slowdown of cell division rates in old age
Clearer understanding of lower cell replication rates in old age may have implications for preventing cancer and slowing aging JOHNS HOPKINS MEDICINE In a novel study comparing healthy cells from people in their 20s with cells from people in their 80s, researchers at the Johns Hopkins Kimmel Cancer Center say they have documented that cell...
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