by Anastasia Lyon, University of Kentucky Par-4-/- mice show increased fat mass and adipocyte hypertrophy. (A) Age- and sex-matched Par-4-/- mice are significantly heavier than Par-4+/+ counterparts. Weight gain in female (n=8-13) and male mice (n=8) was determined over the indicated observation period; representative images of 16-month-old male mice are shown. (B) Par-4-/- mice show increased fat mass. Echo-MRI...
