by Massachusetts General Hospital Longitudinal tau PET imaging measures in an APOE3ch homozygote. A Surface rendering of tau PET (Flortaucipir) images (standardized uptake value ratio, SUVr), at baseline, 3-year follow-up (center), and B rate of change (expressed as %/year), in the APOE3ch homozygote, (left) a typical PSEN1-E280A impaired carrier (center) and a sporadic AD case (right)....