Both cabotegravir and oral tenofovir/emtricitabine (TDF/FTC) have high efficacy for pre-exposure prophylaxis (PrEP) DURHAM, N.C. – Researchers from the HIV Prevention Trials Network (HPTN) announced today that the HPTN 083 clinical trial showed that a pre-exposure prophylaxis (PrEP) regimen containing long-acting cabotegravir (CAB LA) injected once every 8 weeks was superior to daily oral tenofovir/emtricitabine...
Tag: <span>prevention</span>
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Cold War antiseptic has potential in fight against drug-resistant germs and viruses
by Matthew McKenzie, University of Manchester A little-known non-toxic antiseptic developed in the Soviet Union during the Cold War has enormous potential to beat common infections, say University of Manchester scientists. Miramistin, developed for the Soviet Space Program and little known in the West, can inhibit or kill influenza A, human papilloma viruses that cause...
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‘Brutal Pandemic Reality Check’: Top CDC Official Gives Grim Assessment on Coronavirus Containment
By Andrea Germanos, staff writer CDC principal deputy director Dr. Anne Schuchat said we’re “not even beginning to be over this.” Dr. Anne Schuchat, principal deputy director of the Centers for Disease Control and Prevention, testifies before the Senate Health, Education, Labor and Pensions Committee during a hearing on “An Emerging Disease Threat: How the...
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Exercise can slow or prevent vision loss, study finds
EXERCISE CAN SLOW OR PREVENT THE DEVELOPMENT OF MACULAR DEGENERATION AND MAY BENEFIT OTHER COMMON CAUSES OF VISION LOSS, SUCH AS GLAUCOMA AND DIABETIC RETINOPATHY, ACCORDING TO NEW RESEARCH FROM… view more CREDIT: DAN ADDISON | UVA COMMUNICATIONS Exercise can slow or prevent the development of macular degeneration and may benefit other common causes of...
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Osmotic stress identified as stimulator of cellular waste disposal
IMAGE OF MOUSE ASTROCYTES SHOWING THE ACTIN CYTOSKELETON (RED) AND LYSOSOMES (GREEN) view more CREDIT: TANIA LOPEZ-HERNANDEZ Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system. This recycling process...
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A new mechanism of toxicity in Alzheimer’s disease revealed by the 3-D structure of protein
by Institute for Research in Biomedicine (IRB Barcelona) The amyloid precursor protein (APP) is inserted into the cell membrane of neurons. After sequential cleavage by β- and ?-secretases, the Aβ protein (in green) is released.The membrane oligomers are formed by 4 or 8 copies of the Aβ protein. The physicochemical properties of the edges of...
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BALDNESS MAY BE A RISK FACTOR FOR COVID-19
Two small studies published recently suggested most men hospitalized with Covid-19 are bald, generating headlines around the world. While this may sound strange, science does offer a plausible explanation. Male pattern baldness is associated with high levels of male sex hormones called androgens. And androgens seem to play an important role in the entry of...
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New adjuvant successful in extending immunity against HIV
ATLANTA – Researchers at the Yerkes National Primate Research Center and the Emory Vaccine Center (EVC) are first to show a new adjuvant, 3M-052, helps induce long-lasting immunity against HIV. The study results are published today in Science Immunology. In this pre-clinical study that included 90 rhesus monkeys, the researchers showed 3M-052, a new, synthetic...
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Should nursing home residents nearing the end of life continue taking statins?
Journal of the American Geriatrics Society Research Summary AMERICAN GERIATRICS SOCIETY Cardiovascular disease (also called heart disease) is one of the most common medical conditions older adults face. In nursing homes, almost half of all older adult residents have been diagnosed with problems affecting the heart and/or blood vessels. In spite of this, we know...
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Should diabetes treatment lessen for older adults approaching the end of life?
Journal of the American Geriatrics Society Research Summary AMERICAN GERIATRICS SOCIETY One in four people aged 65 or older has diabetes. The disease is the seventh leading cause of death in the United States and a major contributor to heart disease. Experts have recommended that the best way to slow the progression of diabetes–and help...