by City of Hope National Medical Center Effects of WBM extract on tumor growth in TRAMP-C2 flank tumor xenograft models. Credit: Clinical and Translational Medicine (2024). DOI: 10.1002/ctm2.70048 Researchers at City of Hope now understand why taking an investigational white button mushroom supplement shows promise in slowing and even preventing prostate cancer from spreading among men who joined...
Tag: <span>Prostate cancer</span>
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Synthetic vitamin K precursor found to slow progression of prostate cancer in lab mice
by Bob Yirka , Medical Xpress Dietary pro-oxidant therapy using a vitamin K precursor. Credit: Science (2024). DOI: 10.1126/science.adk9167 A team of molecular biologists and other medical specialists at Cold Spring Harbor Laboratory in New York, working with a large number of international partners, reports evidence that a synthetic vitamin K precursor can be used to slow...
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New insights show ASCL1’s role in neuroendocrine prostate cancer, an aggressive and treatment-resistant type
by Jim Stallard, Memorial Sloan Kettering Cancer Center Molecular characterization of PtPM and RPM primary prostate tumor transplants demonstrates emergence of neuroendocrine carcinoma marker expression. Credit: Nature Cancer (2024). DOI: 10.1038/s43018-024-00838-6 A scientist whose discoveries about prostate cancer have led to lifesaving treatments is now shedding light on an emerging and deadlier form of the disease: neuroendocrine prostate...
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What is stereotactic radiation therapy for prostate cancer? How does it compare to other treatments?
by Sathana Dushyanthen and David Kok, The Conversation Comparison of differences between traditional radiotherapy and stereotactic radiotherapy. Credit: Precision Radiation Oncology Prostate cancer is Australia’s most commonly diagnosed cancer. One in six men will be diagnosed by the time they turn 85. Cancers are abnormal groups of cells that grow uncontrollably and start invading neighboring sites. They can also spread to...
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Vitamin K supplement slows prostate cancer in mice, researchers discover
by Cold Spring Harbor Laboratory A new study from Cold Spring Harbor Laboratory Professor Lloyd Trotman and colleagues, published in Science, shows that menadione significantly slows prostate cancer growth in mice and in human-derived cancer cells, as seen here. Credit: Trotman lab/Cold Spring Harbor Laboratory Prostate cancer is a quiet killer. In most men, it’s treatable. However,...
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Researchers evaluate beneficial effects of fermented black garlic extract on prostate cancer
Effects of aged black garlic water extract (ABGE) on cell proliferation of control prostate (PNT-2) (a), androgen-dependent (LNCaP) (b), and androgen-independent (PC-3) (c) prostate cancer (PCa) cells. Cell proliferation and growth were evaluated by resazurin reagent after incubation for 24, 48, and 72 h of PNT-2, LNCaP, and PC-3 cell lines with ABGE at different...
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Protein NSD2 found to drive early prostate cancer development
September 9, 2024 by University of Michigan Prostate cancer cells. Credit: NIH Image GalleryResearchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason that a typically normal protein goes awry and fuels cancer. They found that the protein NSD2 alters the function of the androgen receptor, an important regulator of...
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Q&A: Prostate cancer surge predicted over next 15 years
September 5, 2024 by Stephanie Winn, UC Davis Credit: CC0 Public Domain An estimated one in eight men at some point will get prostate cancer. Those statistics are expected to surge in the next 15 years partly due to the Baby Boomer generation reaching the age when prostate cancer is most common. Millennials won’t be...
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Proof-of-principle study uncovers promising treatment for incurable prostate cancer
September 2, 2024 by Flinders University CDK9 is commonly over-expressed and amplified in prostate cancer. Credit: British Journal of Cancer (2024). DOI: 10.1038/s41416-024-02810-8Researchers from Flinders University and University of South Australia have unveiled a promising new strategy that could be used to treat the most aggressive forms of prostate cancer. Their study, published in British...
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Prostate cancer blood test equally effective across ethnic groups
JULY 22, 2024 by Karolinska Institutet Credit: Karolina Grabowska from PexelsThe Stockholm3 blood test, developed by researchers at Karolinska Institutet, is equally effective at detecting prostate cancer in different ethnic groups, a new paper published in the Journal of Clinical Oncology reports. The test produces significantly better results than the current PSA standard. Stockholm3, a...