Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research. In the first use of canines in an advanced prostate cancer study, scientists explored the pathways used by the cancer to evade the immune system and...
Tag: <span>Prostate cancer</span>
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New blood test combined with image-based prostate cancer screening reduces harms and costs
The combination of a novel blood test and magnetic resonance imaging (MRI) can reduce overdiagnosis of low-risk cancers as well as societal costs in prostate cancer screening, according to a cost-effectiveness study from Karolinska Institutet published in the journal European Urology. The results provide support for organised prostate cancer testing in Sweden, researchers say. A barrier to...
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PSMA PET validates EAU classification system to determine risk of prostate cancer recurrence
JANUARY 21, 2022 by Society of Nuclear Medicine and Molecular Imaging PET disease extent in EAU BCR low-risk patients, EAU BCR high-risk patients, and BCP patients (A) and predictors of PET M1 disease (B). OR = odds ratio. Credit: Justin Ferdinandus, Wolfgang P. Fendler, Andrea Farolfi, et al. New research has confirmed the accuracy of...
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Early prostate cancers can harbor aggressive tumor cells
by Sarah Avery, Duke University Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia Many cases of early prostate cancer are dominated by cells that are slow-growing, often leading to a clinical decision to monitor for progression before initiating treatments that can have adverse side effects. But some of these...
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Researchers show increased survival rate in prostate cancer patients with addition of hormone therapy treatments
UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER IMAGE: “OUR GOAL IS TO BETTER PERSONALIZE THERAPY FOR PROSTATE CANCER PATIENTS, BY PROVIDING THE MOST PRECISE AND ACCURATE ESTIMATES OF THE BENEFIT OF HORMONE THERAPY.” ~ SENIOR AUTHOR, DANIEL E. SPRATT, MD. CREDIT: UNIVERSITY HOSPITALS CLEVELAND–Prostate cancer is the leading cause of cancer in men worldwide, and radiotherapy is...
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Large international evaluation shows AI accurately diagnoses prostate cancer
by Karolinska Institutet Prostate cancer cells. Credit: NIH Image Gallery Researchers at Karolinska Institutet in Sweden have together with international collaborators completed a comprehensive international validation of artificial intelligence (AI) for diagnosing and grading prostate cancer. The study, published in Nature Medicine, shows that AI systems can identify and grade prostate cancer in tissue samples from...
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UCI-led research team discovers a molecular feature in prostate cancer with prognostic value, distinguishes ancestral differences
UNIVERSITY OF CALIFORNIA – IRVINEP IMAGE: PLOTS FOR BIOCHEMICAL RELAPSE STRATIFIED BY PROGNOSTIC MODELS BASED ON CLINICAL DATA ALONE (TOP) OR CLINICAL DATA PLUS AN ERV PANEL (BOTTOM). “WE FOUND THAT THE COMBINATION OF ERVS AND CLINICAL INFORMATION OUTPERFORMED PREDICTION MODELS BASED ON CLINICAL PROGNOSTICATORS ALONE,” SAYS FARAHNAZ RAHMATPANAH, PHD, ASSISTANT PROFESSOR IN RESIDENCY IN...
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Abiraterone could cut the risk of prostate cancer death in half for some patients
Prostate cancer is a deadly condition, even though new effective treatments are emerging. It is actually the second most common cancer in men worldwide and the incidence rate of this disease is around 1.1-1.5 per 1000 men every year. Now scientists at UCL found that a new prostate cancer drug abiraterone could halve risk of prostate cancer death...
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Thousands of men battling prostate cancer could be cured with a ‘game-changing’ HOUR-long operation that uses electrical currents to destroy tumours
By STEPHEN MATTHEWS HEALTH EDITOR FOR MAIL PUBLISHED: 03:37 EST, 3 January 2022 | UPDATED: 08:36 EST, 3 January 2022 Thousands of men with prostate cancer in the UK could be cured with an hour-long operation, doctors hope. The ‘game-changing’ treatment uses electrical currents to destroy difficult to reach tumours. Surgery to remove the prostate or radiotherapy are the...
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Although diagnosed with higher-risk prostate cancer, Black men undergoing radiation have better outcomes than white men
by University of California, Los Angeles Credit: Pixabay/CC0 Public Domain UCLA Jonsson Comprehensive Cancer Center researchers leading a meta-analysis of seven randomized trials found an “unexpected result”: Although Black men appeared to have more aggressive disease when they enrolled in clinical trials of radiation therapy for prostate cancer, their treatment outcomes and disease-specific outcomes were...