At a GlanceMen with cancer confined to the prostate experienced different long-term side effects depending on the type of treatment received.Understanding the pros and cons of different treatments may help men and their health care teams make more informed treatment decisions.Doctor showing something on a clipboard to a senior man.The choice of treatment for prostate...
by Vanderbilt University Medical Center Credit: Unsplash/CC0 Public DomainA 10-year follow-up study of nearly 2,500 U.S. men who received prostate cancer treatment will help inform decision-making in terms of treatments and side effects for a diverse population. The CEASAR (Comparative Effectiveness Analysis of Surgery and Radiation for Localized Prostate Cancer) study, coordinated by Vanderbilt University Medical...
by Albert Ludwigs University of Freiburg Identification of a bi-substrate inhibitor of KMT9. a Chemical structure of compound 1a with predicted binding mode. b MST assay to determine the dissociation constant (Kd) of compound 1a and SAM binding to KMT9. c FTSA for compound 1a binding to KMT9. d Chemical structure of SAM. e FTSA for...
Many of the most potent human oncoproteins belong to a class of proteins called transcription factors, but designing small molecule drugs that target transcription factors is a major challenge, especially when treating aggressive forms of prostate cancer. An international team of researchers from the Institute for Research in Biomedicine in Barcelona, the Max Planck Institute...
by Keck School of Medicine of USC Credit: CC0 Public Domain A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk—451 in all—through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet. The research, led by the USC Center for...
by Brigham and Women’s Hospital Credit: Unsplash/CC0 Public Domain Men with high-grade prostate cancer and low prostate-specific antigen (PSA) levels have a poor prognosis. The question remains as to whether the chemotherapy drug docetaxel, which increases survival in metastatic prostate cancer, can improve the cure rate in these patients. In a new study by investigators from...
Neil Osterweil October 04, 2023 SAN DIEGO — With just five fractions of stereotactic body radiation therapy (SBRT), men with low- or intermediate-risk prostate cancer can have 5-year disease control as good as that provided by conventional external-beam radiation therapy delivered at higher doses in 20-39 fractions, according to new data from the phase 3 randomized PACE-B...
Andy Willis, 51, was handed a lifeline after being diagnosed with prostate cancer By ETHAN ENNALS PUBLISHED: 17:50 EDT, 21 October 2023 | UPDATED: 21:08 EDT, 22 October 2023 A man given only years to live after he was diagnosed with aggressive and incurable prostate cancer is now close to being tumour-free just months after he began a revolutionary drug...
Ability to reverse cancer’s resistance to therapy opens possibility of treatment for late-diagnosed men Andrew Gregory Health editor Scientists say a new way to treat prostate cancer may be on the horizon after finding it is possible to reverse its resistance to therapy. More than a million men worldwide are diagnosed with the disease each year....
by Lisette Hilton, University of Miami Dr. Bruno Nahar says his experience with HIFU has taught him the importance of patient selection, as the procedure isn’t “one size fits all.” Credit: Desai Sethi Urology InstituteFor Bruno Nahar, M.D., urological oncologist at Sylvester Comprehensive Cancer Center and Desai Sethi Urology Institute, performing the 150th focal high-intensity focused...
