by H. Lee Moffitt Cancer Center & Research Institute BTN expression and spontaneous gamma/delta T cell infiltration in prostate tumors. (A) Bioinformatic analysis of TCR gamma variable regions (TRGV), BTN3A1, BTN2A1, ULBP1, MICA, MICB, and PSCA in bone and soft tissue biopsies from 118 individuals with mCRPC (SU2C/PCF dataset). (B) Specific comparison of TRGV expression in bone metastases....
by Cedars-Sinai Medical Center Credit: CC0 Public Domain Vitamin D deficiency could be the reason African American men experience more aggressive prostate cancer at a younger age compared with European American men, new research from Cedars-Sinai Cancer suggests. The multi-institutional study, published today in Cancer Research Communications, could pave the way for revised nutritional guidelines. While...
by Elana Gotkine For patients with noncastrate advanced prostate cancer, docetaxel, abiraterone, enzalutamide, apalutamide, or darolutamide are each recommended as standards of care with androgen deprivation therapy (ADT), and doublet therapy is inferior to triplet therapy, according to a guideline update published online April 3 in the Journal of Clinical Oncology. Katherine S. Virgo, Ph.D., from the Rollins...
by Carla K. Johnson This 1974 microscope image made available by the Centers for Disease Control and Prevention shows changes in cells indicative of adenocarcinoma of the prostate. A study published by the New England Journal of Medicine on Saturday, March 11, 2023, finds long-term evidence that actively monitoring prostate cancer can be a safe...
by European Association of Urology Credit: Pixabay/CC0 Public Domain An advanced imaging method is showing promise as a way to improve the diagnosis of prostate cancer by giving clinicians a clearer view of suspected tumors during biopsy. A trial conducted at the University Hospital Bonn, in Germany, has been testing the benefit of a scanning...
by University of Chicago Medical Center Credit: Unsplash/CC0 Public Domain Immunotherapies have been successful in treating many cancer conditions; however, not much success has yet been achieved in metastatic castrate-resistant prostate cancer (mCRPC). A study published March 2 in Clinical Cancer Research has revealed new insights into why immunotherapies don’t tend to work as well in prostate cancer....
KECK SCHOOL OF MEDICINE OF USC Prostate cancer takes a greater toll on Black men than on men of other races. In the United States, one in six Black men will get prostate cancer in their lifetime, compared to one in eight men overall. Black men are also more than twice as likely to die...
by Elsevier Credit: Pixabay/CC0 Public Domain Predicting the course of prostate cancer is challenging because only a fraction of prostate cancer patients experience recurrence after radical prostatectomy or radiation therapy. Yet, prostate cancer remains one of the most fatal malignancies in men in the United States. Now, investigators have developed a machine learning model that...
by University of East Anglia Prostate cancer cells. Credit: NIH Image Gallery Researchers at the University of East Anglia have helped develop a new blood test to detect prostate cancer with greater accuracy than current methods. New research shows that the Prostate Screening EpiSwitch (PSE) blood test is 94 percent accurate—beating the currently used prostate-specific...
by Sanford Burnham Prebys Medical Discovery Institute Prostate cancer cells. Credit: NIH Image Gallery For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα. The findings, published recently in Science Advances, could help address the growing threat of treatment resistance in prostate cancer and could also lead to...
