Scripps Research collaborators develop a way to seamlessly create the compound’s complex structure SCRIPPS RESEARCH INSTITUTE CHEMISTS HANS RENATA, PHD, AND ALEXANDER ADIBEKIAN, PHD, BOTH OF SCRIPPS RESEARCH, SAY THE BACTERIAL EXTRACT CEPAFUNGIN I IS IN THE SAME CLASS AS SEVERAL FDA-APPROVED ANTI-CANCER DRUGS, WITH SOME… view more CREDIT: SCRIPPS RESEARCH JUPITER, FL–Scripps Research chemists...
by Harvard Medical School The aberrant buildup of misfolded proteins is a hallmark of a host of disorders, including neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Aggregates of these toxic proteins wreak havoc on the function of cells, tissues, and organs, and despite intensive research over many decades, there are still no effective means to...
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases. Although they are not alive themselves, proteins nonetheless progress through a life cycle of sorts: they are created by the cell, serve a specific purpose in the organism, and ultimately expire either by...
