The finding could eventually lead to possible therapies for the especially dangerous melanoma and pancreatic adenocarcinoma, as well as the most common type of childhood brain cancer and adult skin cancer. The study appears in the journal Life Science Alliance. The discovery concerns the GLI1 protein, which is important in cell development but has also been found...
Tag: <span>Protein</span>
Post
DeepMind found the structure of nearly every protein known to science
By Nicole Wetsman Jul 28, 2022, 7:00am EDT A protein structure identified by AlphaFold. Image: DeepMind DeepMind is releasing a free expanded database with its predictions of the structure of nearly every protein known to science, the company, a subsidiary of Google parent Alphabet, announced today. DeepMind transformed science in 2020 with its AlphaFold AI software, which produces highly accurate...
Post
How to turn muscle into a protein factory for advanced gene therapy
by Daegan Miller, University of Massachusetts Amherst Lila Gierasch (center), professor of biochemistry and molecular biology at UMass Amherst. Credit: UMass Amherst In a major new development in the quest to develop better gene therapies with which to treat a host of diseases, researchers at the University of Massachusetts Amherst and UMass Chan Medical School recently...
Post
Coronavirus spike protein activated natural immune response, damaged heart muscle cells
by American Heart Association Credit: Pixabay/CC0 Public Domain Heart damage is common among patients hospitalized with COVID-19, leading many to wonder how the virus affects the heart. Now, researchers have found that the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can lead to heart muscle injury through the inflammatory process, according...
Post
Copper leads to protein aggregation in Parkinson’s disease
by Rainer Klose, Swiss Federal Laboratories for Materials Science and Technology Images taken with an atomic force microscope show alpha-synuclein in the form of fibrils (left). When the protein is placed in a solution containing copper, ring-like structures form instead (right). Credit: Empa Copper exposure in the environment and the protein alpha-synuclein in the human brain...
Post
Protein changes in cerebrospinal fluid indicate inflammatory processes in the brain
by Universitaet Tübingen Credit: Pixabay/CC0 Public Domain Alzheimer’s, Parkinson’s and other neurodegenerative diseases are associated with inflammatory processes in the brain. German researchers have succeeded in identifying a group of proteins in cerebrospinal fluid that could provide information about such inflammatory processes. As so-called biomarkers, the proteins could help researchers to better understand disease processes in...
Post
Protein linked to intellectual disability has complex role
by Washington University School of Medicine Researchers at Washington University School of Medicine in St. Louis have identified a previously unknown function for the fragile X protein, the loss of which is the leading inherited cause of intellectual disability. The researchers showed that the protein modulates how neurons in the brain’s memory center process information,...
Post
A diet rich in protein, zinc and niacin and low in saturated fat makes blood vessels more flexible, Israeli research suggests
EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY A new study being presented at the European Congress on Obesity (ECO) in Maastricht, the Netherlands (4-7 May), has linked key nutrients, including protein, zinc and niacin, to improvements in heart health. Improvements in metabolic and cardiovascular health seen during weight loss in people with obesity are traditionally...
Post
How it works: The protein that stimulates muscle growth
by Laurie Fickman, University of Houston Credit: CC0 Public Domain In the gym, you are not just pumping iron, you are oxygenating muscle cells which keeps those muscles healthy, strong and growing—a process called hypertrophy, or an increase in muscle mass due to an increase in muscle cell size. Conversely, under the covers, lounging, your...
Post
The protein that keeps the pancreas from digesting itself
by Salk Institute Left: Healthy pancreas. Right: Extensive pancreatic scarring (purple) when ERR gamma is lost from acinar cells. Credit: Salk Institute Every day, your pancreas produces about one cup of digestive juices, a mixture of molecules that can break down the food you eat. But if these powerful molecules become activated before they make...