by Julie Langelier, Gladstone Institutes Credit: CC0 Public Domain With the school year well on its way, we all recognize the importance of getting students energized. However, we also know that overstimulated children can wreak havoc on a classroom, leaving a teacher trying to regain control of their group. The situation is very similar in the...
by Northwestern University Credit: Unsplash/CC0 Public Domain A Northwestern Medicine study in mice has identified new treatment targets for glaucoma, including preventing a severe pediatric form of glaucoma, as well as uncovering a possible new class of therapy for the most common form of glaucoma in adults. In people with high pressure glaucoma, fluid in the...
by Daegu Gyeongbuk Institute of Science and Technology (DGIST) Using cell-based and animal model-based experiments, scientists from DGIST, Korea have deciphered how prostate cancer progresses into the fatal and difficult-to-treat malignant stage. Credit: Kateryna Kon from Shutterstock Prostate cancer (PC) is one of the leading causes of global cancer-related deaths among men. While a standard...
by Mette Haagen Marcussen, Technical University of Denmark Fig. 1: Experimental overview of our scMS workflow. a Overview of the hierarchical nature of an Acute Myeloid Leukemia hierarchy, with leukemic stem cells (LSC) at the apex, differentiating into progenitors, and subsequently, blasts. b FACS plot of the OCI-AML8227 hierarchy according to their CD34/CD38 surface marker expression...
by University of Illinois at Chicago Credit: Pixabay/CC0 Public Domain A new study by University of Illinois Chicago researchers shows a mechanism that stops the herpes simplex virus 1 from causing serious brain damage and death. Researchers discovered a function of a protein complex, mammalian target of rapamycin complex 2, in an antiviral defense mechanism. This protein complex limits...
by Bob Yirka , Medical Xpress Fig. 1. Discovery of the hit compound CPD1 and chemical lead HB007.(A) Workflow in LN229 cell–based drug screening of the NCI library through Western blots and cell viability assay with the identification of 11 active compounds with D5 characterized as the hit compound (highlighted in red). (B) The chemical...
Tom Edwardson modified a tiny artificial protein structure so it could be used as a vehicle for RNA molecules and other active substances. He now aims to create a spin-off to bring his development to market. Tom Edwardson holds up a 3D-printed model of his protein cage. The actual cages are three million times smaller....
EUROPEAN COLLEGE OF NEUROPSYCHOPHARMACOLOGY Type of research: not peer reviewed/experimental study/animal work Researchers have discovered that a particular protein can be used as a brain marker to indicate whether emotional memories can be changed or forgotten. This is a study in animals, but the researchers hope that the findings will eventually allow people suffering from...
by Will Doss, Northwestern University Fig. 1: Single-cell RNA sequencing profiles comparing breast cancer cells from primary and metastatic tumor sites. a A schematic showing the single-cell RNA sequencing of the sorted cells from L2T- or L2G-labeled TNBC PDX (mice 1 and 2) or MDA-MB-231 tumor (mouse 3)-bearing mice, both primary breast tumors and lung metastases...
IMAGE: SAMANTHA MENDONSA (LEFT) AND MARINA CHEKULAEVA (RIGHT) IN THE LAB AT BIMSB / MDC CREDIT: CHEKULAEVA LAB, MDC Charcot-Marie-Tooth disease (CMT) is a rare hereditary condition. It occurs when genetic changes disrupt the transmission of nerve signals from the brain to the muscles of the extremities, particularly those of the lower limbs. This leads...
