by Cold Spring Harbor Laboratory Pancreatitis is an inflammation of the pancreas that accounts for 275,000 hospitalizations in the United States annually. Patients who suffer from hereditary pancreatitis have a 40 to 50 percent lifetime risk of developing pancreatic cancer. Dannielle Engle, a former Cold Spring Harbor Laboratory (CSHL) Cancer Center postdoctoral fellow who was recently appointed Assistant Professor...
Tag: <span>proteins</span>
Post
Blood stem cells produced in vast quantities in the lab
A glue ingredient was the secret to getting the mouse cellsto multiply outside the body. Researchers have managed to grow large numbers of blood-forming stem cells in the lab using a surprisingly simple ingredient found in glue. And when injected into mice, the cells started producing key components of blood. “The finding is very unexpected and...
Post
Team gets a closer look at how proteins meet on the cell membrane
JUPITER, FL – Oct. 10, 2018 – Scripps Research scientists have uncovered the workings of a critical process in cell survival. Their study, published recently in the Proceedings of the National Academy of Sciences, is the first to show exactly how a protein called talin activates another critical protein, called integrin, to do its job...
Post
Analytical tool predicts genes that can cause disease by producing altered proteins
BAYLOR COLLEGE OF MEDICINE Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers, including researchers from Baylor College of Medicine, that has developed a new analytical tool...
Post
Study identifies protein’s role in mediating brain’s response to stress
A study led by Massachusetts General Hospital (MGH) investigators has identified a critical role for a protein called Kruppel-like factor 9 (Klf9) in the brain’s response to stress, which has implications for protecting against the effects of stress in conditions like major depression and post-traumatic stress disorder (PTSD). In their paper published in Cell Reports, the...
Post
Enzyme found to control formation of collagen carriers and inhibit collagen secretion
Researchers at Tokyo Institute of Technology (Tokyo Tech) have identified an enzyme that controls how much our cells secrete collagen. As collagen imbalance is linked to a range of human diseases, the study provides clues to new therapeutic strategies. Moreover, the findings could facilitate efficient production of collagen for the food, cosmetic and pharmaceutical industries. IMAGE: ELECTRON...