ALPHAMED PRESS CO-AUTHORS SO GUN HONG, DVM, PH.D., AND CYNTHIA DUNBAR, M.D., OF THE NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI), PART OF THE NATIONAL INSTITUTES OF HEALTH.view more CREDIT: ALPHAMED PRESS Durham, NC – A new platform reported on today in STEM CELLS Translational Medicine (SCTM) will enable long-term tracking of cardiomyocytes produced from...
Rathke’s cleft cysts are benign, fluid-filled growths that develop in the pituitary gland, a small oval-shaped gland near the underside of the brain. Usually, these cysts don’t cause symptoms. However, if they become large enough to compress the organ and surrounding tissues, then they can cause problems with vision and the secretion of hormones from...
An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online in The New England Journal of Medicine. The ongoing Phase 1 trial is supported by the National Institute of Allergy...
For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, National Institutes of Health researchers report for the first time that ancient viral genes that were once considered “junk DNA” may play...
Mass. General team’s findings may have application to treatment of cancer, neurodegenerative disorders MASSACHUSETTS GENERAL HOSPITAL Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which cells sense dysfunction of the proteasome – a cellular component that degrades unneeded or defective proteins – and respond in a previously undescribed manner, by editing the amino acid sequence of a key sensing protein....
by National Institutes of Health Two proteins that bind to stress hormones work together to maintain a healthy heart in mice, according to scientists at the National Institutes of Health and their collaborators. These proteins, stress hormone receptors known as the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), act in concert to help support heart...
RUHR-UNIVERSITY BOCHUM Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal. In collaboration with the neurology department at the Ruhr-Ubiversität’s St. Josef-Hospital as well as colleagues at the Max Planck Institute of Biochemistry in Martinsried, an interdisciplinary team under the...
In October 2010, an Italian religious historian named Alberto Melloni stood over a small cherrywood box in the reading room of the Laurentian Library, in Florence. The box was old and slightly scuffed, and inked in places with words in Latin. It had been stored for several centuries inside one of the library’s distinctive sloping...
Our cognitive abilities come down to how well the connections, or synapses, between our brain cells transmit signals. Now a new study by researchers at MIT’s Picower Institute for Learning and Memory has dug deeply into the molecular mechanisms that enable synaptic transmission to show the distinct role of a protein that, when mutated, has been linked to causing intellectual disability. The key protein, called...
To understand what therapeutics could benefit aging and DNA damage, we have to consider what molecules are involved. So, what do we know about this process? There are a number of factors that are involved in the aging process. Many things such as diet, lifestyle, medication, genetics, diseases, amongst countless others, are involved. However, in...
