Harish Seethapathy, M.B.B.S., from Massachusetts General Hospital in Boston, and colleagues examined the frequency, severity, etiology, and predictors of AKI among patients receiving checkpoint inhibitor therapy from May 2011 to December 2016. Data were included for 1,016 patients (average age, 63 years). The researchers found that overall, 17 percent of patients receiving checkpoint inhibitor therapy...
Tag: <span>proton pump inhibitors (PPIs)</span>
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36% of proton pump inhibitor prescriptions for older adults may be unnecessary
by Enrique Rivero, University of California, Los Angeles One in eight older adults was prescribed proton pump inhibitor drugs, which are used to treat gastric ulcers or to prevent gastrointestinal bleeding in those taking blood thinners. About 36 percent of those prescriptions were potentially unnecessary, a study found, primarily because people took them far longer...
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Research ties common heartburn medications to kidney disease and failure
Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study. Use of proton pump inhibitors (PPI), a group of drugs that reduce the production of stomach acid, increases the risk of chronic kidney disease by 20 percent and raises the risk of kidney failure by four times. Risks were highest...
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Some heartburn drugs linked with higher risk of death
Some heartburn drugs used by millions of Americans are associated with a higher risk of death, a new study suggests, but people on the drugs should talk with their doctor first before stopping the medicines, experts say. The drugs, called proton pump inhibitors (PPIs), reduce stomach acid and are available over-the-counter and by prescription. Other recent...