LA JOLLA INSTITUTE FOR IMMUNOLOGY IMAGE: THE CROFT LAB CAPTURED HOW THE PROLIFERATION OF SKIN CELLS, AS SEEN IN PSORIASIS (INDICATED WITH PURPLE STAINING), DECREASED WHEN TWEAK ACTIVITY WAS BLOCKED. CREDIT: RINKESH GUPTA, LA JOLLA INSTITUTE FOR IMMUNOLOGY LA JOLLA—About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of...
Tag: <span>Psoriasis</span>
For psoriasis, molecular signature in healthy-appearing skin may be best predictor of response to anti-TNF treatment
It’s common for people with psoriasis to develop dry, inflamed skin lesions. However, the normal-appearing skin may hold the key to predict whether certain medications will work for patients. A Michigan Medicine study, published in the Journal of Allergy and Clinical Immunology, analyzed patients with chronic plaque psoriasis being treated with etanercept, a drug used to reduce...
Glycerin is safe, effective in psoriasis model
by Medical College of Georgia at Augusta University Dr. Wendy Bollag and first author Dr. Vivek Choudhary, MCG physiologist and molecular biologist. Credit: Michael Holahan, Augusta University Patients with psoriasis have reported that glycerin, an inexpensive, harmless, slightly sweet liquid high on the list of ingredients in many skin lotions, is effective at combatting their psoriasis...
Certain Biologics May Boost Serious Infection Risk in Patients With Psoriasis
NEW YORK (Reuters Health) —Psoriasis patients who are new users of infliximab and adalimumab appear to be at a greater risk of serious infection than those beginning therapy with etanercept, according to French researchers. In an online paper in JAMA Dermatology, Dr. Emilie Sbidian of Hôpital Henri Mondor, Creteil, and colleagues note that biologics, as...
Skin-buzzing sensor detects psoriasis and potentially other disorders
By Ben Coxworth May 31, 2021 The prototype works on both hair-bearing and hairless skin Dr. Yu Xinge’s team When someone has a problematic skin condition, the affected skin is typically either stiffer or softer than normal. A new sensor has been shown to detect such differences, potentially allowing doctors to diagnose problems more quickly...
New factor in the development of psoriasis discovered
by Medical University of Vienna Credit: Estzer Miller on Pixabay Psoriasis is a common inflammatory skin condition. The underlying genetic factors have not yet been sufficiently researched. The skin inflammation is usually triggered by external factors such as infections or stress. A research team at the Institute of Cancer Research of the Medical University of Vienna has now managed to...
Biologic therapy for psoriasis may reduce heart disease
by American Heart Association Human heart. Credit: copyright American Heart Association Patients with psoriasis treated with biologic therapy, which are protein-based infusions to suppress inflammation, had a significant reduction in high-risk plaque in heart arteries, over one-year, according to new research published today in Circulation: Cardiovascular Imaging, an American Heart Association journal. Chronic inflammation in people with...
Study uncovers link between psoriasis and joint disease
Reviewed by James Ives, M.Psych. (Editor) A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure. The researchers found that an overabundance of a protein known as KLK6 can produce and worsen the skin inflammation characteristic...
Severity of psoriasis related to the severity of non-alcoholic fatty liver disease
by EADV New results from a prospective, 12-month study indicate that the severity of psoriasis is associated with the severity of non-alcoholic fatty liver disease (NAFLD). Patients with psoriasis and NAFLD had more severe hepatic damage, if they had a higher severity of psoriasis, based on ultrasound elastography measurements. The study findings were presented today...
Study: Some biologic treatments for psoriasis may be safer for patients
by Beth Israel Deaconess Medical Center A common chronic skin condition affecting 125 million people worldwide, psoriasis is an autoimmune disease, a class of disorders in which the immune system attacks the body’s own healthy cells. In recent years, new medications—known as biologics—that inhibit the overactive immune system by targeting specific inflammatory pathways, have revolutionized the treatment of psoriasis and...