Megan Brooks May 13, 2024 It’s becoming clear that adolescent brain is particularly vulnerable to cannabis, especially today’s higher-potency products, which put teens at risk for impaired brain development; mental health issues, including psychosis; and cannabis use disorder (CUD). That was the message delivered by Yasmin Hurd, PhD, director of the Addiction Institute at Mount...
Tag: <span>Psychosis</span>
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AI Tool May Help Predict Psychosis Before It Occurs
Megan Brooks The onset of psychosis in individuals at clinical high risk (CHR) may be predicted before it occurs using a machine learning tool that classifies MRI brain scans, an international consortium of researchers reported. Prior studies using brain MRI have revealed structural differences in the brain after the onset of psychosis. The new work...
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Could brain mapping transform how we predict and treat psychosis?
by Wellcome Trust Credit: Human Brain ProjectPsychotic disorders affect around one in 100 people globally and are among the most severe mental health problems. Early intervention is crucial to reduce the impact of psychosis, but diagnosis and treatment can be challenging. And despite progress, the underlying mechanisms of psychosis are not fully understood. There’s evidence to...
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Excitatory-inhibitory neurotransmitter imbalance precedes psychosis
by Elsevier Comparison between controls and deletion carriers, GABA+ and Glx levels in: a) Anterior cingulate cortex (ACC), b) Hippocampus and c) Superior Temporal Cortex (STC). Compared to controls, deletion carriers were found to have higher levels of Glx in the hippocampus and STC and lower levels of GABA+ in the hippocampus. The lines in the...
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Protecting the intellectual abilities of people at risk for psychosis
UNIVERSITÉ DE GENÈVE IMAGE: EFFECTS OF SSRIS ON BRAIN AND INTELLECTUAL DEVELOPMENT. ON THE LEFT SIDE: BRAIN MAP SHOWING REGIONS OF THE BRAIN PROTECTED BY THE PROLONGED ADMINISTRATION OF SSRIS COMPRISING A NETWORK OF PREFRONTAL AND LIMBIC STRUCTURES. ON THE RIGHT SIDE: PLOT DISPLAYING AN INCREASE IN IQ SCORES IN SUBJECTS TREATED WITH SSRIs AS...
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New findings link brain’s immune system to psychosis
by Karolinska Institutet Credit: CC0 Public Domain New research at Karolinska Institutet in Sweden suggests a link between psychosis and a genetic change that affects the brain’s immune system. The study published in Molecular Psychiatry may impact the development of modern medicines for bipolar disorder or schizophrenia. Psychosis affects approximately 2-3% of the population and is characterized by a change...
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Pimavanserin reduced symptoms of dementia-related psychosis in phase 3 trial
A large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in people with dementia, a condition for which no treatments are currently licensed UNIVERSITY OF EXETER A large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced...
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Experimental schizophrenia drug delivers promising human trial results
By : Rich Haridy A newly published article in the New England Journal of Medicine is reporting the successful results of a clinical trial testing an experimental drug designed to treat psychosis in schizophrenia. The drug works unlike any other existing anti-psychotic medication, and without many of their negative side effects. The development of anti-psychotic...
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Psychotic experiences are quite common even among people who don’t have a mental health condition
by Sophie Legge, James Walters and Stanley Zammit, The Conversation Have you ever seen or heard something that turned out not to exist? Or have you ever thought something was happening that no one else noticed—perhaps thinking you were being followed, or that something was trying to communicate with you? If so, you may have...
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CBD reduces impairment caused by cannabis
by University College London The more cannabidiol (CBD) in a strain of cannabis, the lower the impairment to brain function, finds a new UCL-led brain imaging study. The research, published in the Journal of Psychopharmacology, is the first study using fMRI (functional magnetic resonance imaging) to gauge how different strains of cannabis impact brain function. “Over the last two...
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