by University of Rochester Medical Center The four sensory networks of the brain network partition. The partition comprises four sensory networks, with the somatomotor network encompassing the somatosensory cortex. The thalamus contains parcels of each sensory network. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02767-3 The current standard of care for psychosis is a diagnostic interview, but what if it...
Tag: <span>Psychosis</span>
Post
Cannabis disrupts brain activity in young adults prone to psychosis
by McGill University Credit: Unsplash/CC0 Public Domain Young adults at risk of psychosis show reduced brain connectivity, a deficit that cannabis use appears to worsen, a new study has found. The breakthrough paves the way for psychosis treatments targeting symptoms that current medications miss. In the first-of-its-kind study, McGill University researchers detected a marked decrease in...
Post
High-Potency Cannabis Tied to Impaired Brain Development, Psychosis, CUD
Megan Brooks May 13, 2024 It’s becoming clear that adolescent brain is particularly vulnerable to cannabis, especially today’s higher-potency products, which put teens at risk for impaired brain development; mental health issues, including psychosis; and cannabis use disorder (CUD). That was the message delivered by Yasmin Hurd, PhD, director of the Addiction Institute at Mount...
Post
AI Tool May Help Predict Psychosis Before It Occurs
Megan Brooks The onset of psychosis in individuals at clinical high risk (CHR) may be predicted before it occurs using a machine learning tool that classifies MRI brain scans, an international consortium of researchers reported. Prior studies using brain MRI have revealed structural differences in the brain after the onset of psychosis. The new work...
Post
Could brain mapping transform how we predict and treat psychosis?
by Wellcome Trust Credit: Human Brain ProjectPsychotic disorders affect around one in 100 people globally and are among the most severe mental health problems. Early intervention is crucial to reduce the impact of psychosis, but diagnosis and treatment can be challenging. And despite progress, the underlying mechanisms of psychosis are not fully understood. There’s evidence to...
Post
Excitatory-inhibitory neurotransmitter imbalance precedes psychosis
by Elsevier Comparison between controls and deletion carriers, GABA+ and Glx levels in: a) Anterior cingulate cortex (ACC), b) Hippocampus and c) Superior Temporal Cortex (STC). Compared to controls, deletion carriers were found to have higher levels of Glx in the hippocampus and STC and lower levels of GABA+ in the hippocampus. The lines in the...
Post
Protecting the intellectual abilities of people at risk for psychosis
UNIVERSITÉ DE GENÈVE IMAGE: EFFECTS OF SSRIS ON BRAIN AND INTELLECTUAL DEVELOPMENT. ON THE LEFT SIDE: BRAIN MAP SHOWING REGIONS OF THE BRAIN PROTECTED BY THE PROLONGED ADMINISTRATION OF SSRIS COMPRISING A NETWORK OF PREFRONTAL AND LIMBIC STRUCTURES. ON THE RIGHT SIDE: PLOT DISPLAYING AN INCREASE IN IQ SCORES IN SUBJECTS TREATED WITH SSRIs AS...
Post
New findings link brain’s immune system to psychosis
by Karolinska Institutet Credit: CC0 Public Domain New research at Karolinska Institutet in Sweden suggests a link between psychosis and a genetic change that affects the brain’s immune system. The study published in Molecular Psychiatry may impact the development of modern medicines for bipolar disorder or schizophrenia. Psychosis affects approximately 2-3% of the population and is characterized by a change...
Post
Pimavanserin reduced symptoms of dementia-related psychosis in phase 3 trial
A large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in people with dementia, a condition for which no treatments are currently licensed UNIVERSITY OF EXETER A large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced...
Post
Experimental schizophrenia drug delivers promising human trial results
By : Rich Haridy A newly published article in the New England Journal of Medicine is reporting the successful results of a clinical trial testing an experimental drug designed to treat psychosis in schizophrenia. The drug works unlike any other existing anti-psychotic medication, and without many of their negative side effects. The development of anti-psychotic...