by Nagoya University Higher frequencies of two gene variants were associated with a severe skin disease called Generalized pustular psoriasis (GPP). Credit: Reiko MatsushitaA team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis (GPP). The team’s findings, published in the Journal of the...
Megan Brooks September 02, 2022 The US Food and Drug Administration (FDA) has approved the biologic agent spesolimab (Spevigo) for the treatment of flares in adults with generalized pustular psoriasis (GPP), the company has announced. “GPP flares can greatly impact a patient’s life and lead to serious, life-threatening complications,” Mark Lebwohl, MD, principal investigator in the pivotal...
by The Mount Sinai Hospital Credit: CC0 Public Domain Generalized pustular psoriasis (GPP) is a rare, life-threatening skin condition for which there are no approved treatments. It is characterized by episodes of widespread eruptions of painful, sterile pustules (blisters of non-infectious pus). There is a high unmet need for treatments that can rapidly and completely...
