News Release 5-Sep-2024 Peer-Reviewed PublicationTokyo Medical and Dental University Caspase-11 drives interleukin-1β (IL-1β) secretion in paws and affects clinical severity of arthritis in mice infected with Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans)image: Researchers unveil mechanism by which periodontal bacterium A. actinomycetemcomitans exacerbated symptoms of rheumatoid arthritis (RA) conducted various experiments in a mouse model of rheumatoid arthritis...
Tag: <span>RA</span>
Machine learning helps identify rheumatoid arthritis subtypes
SCIENCE & TECHNOLOGY NEWS A machine-learning tool created by Weill Cornell Medicine and Hospital for Special Surgery (HSS) investigators can help distinguish subtypes of rheumatoid arthritis (RA), which may help scientists find ways to improve care for the complex condition. Image credit: Max Pixel, CC0 Public Domain The study, published in Nature Communications, shows that...
Steroid Bridging in RA Gets New Support, but Concerns Remain
Randy Dotinga September 13, 2023 In a new salvo in the dispute over the wisdom of early “bridging” treatment with glucocorticoids in rheumatoid arthritis, Dutch researchers suggested in a new meta-analysis that the American College of Rheumatology guideline is too cautious. The report, published in Annals of the Rheumatic Diseases, examined three randomized trials of...
Mediterranean diet may aid mental health in rheumatoid arthritis patients
JULY 24, 2024 by Lori Solomon Greater adherence to a Mediterranean diet is associated with lower odds of depression in individuals with rheumatoid arthritis, according to a study published online July 5 in the Journal of Health, Population and Nutrition. Liya Ma, from Honghui Hospital at Xi’an Jiaotong University in China, and colleagues explored the...
Socioeconomic factors linked to persistently active rheumatoid arthritis
JULY 22, 2024 by Elana Gotkine Socioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 in RMD Open. Maryam Adas, from the King’s College London Faculty of Life Sciences & Medicine, and colleagues examined which biological and nonbiological factors are associated with pactiveRA or...
Cardiovascular considerations in RA
EUROPEAN ALLIANCE OF ASSOCIATIONS FOR RHEUMATOLOGY (EULAR) The increased cardiovascular risks in RA include acute coronary syndromes (ACS). The extent to which DMARD-induced remission could reduce the risk of ACS in RA versus rates in the general population – and whether there are DMARD-specific beneficial effects on ACS risk – remain unknown. In a session...
Serum IL-35 levels tied to bone loss with rheumatoid arthritis
Yuxuan Li, from the First Affiliated Hospital of China Medical University in Shenyang, and colleagues explored the correlations between IL-35 levels and bone loss in postmenopausal women, including 76 with RA and 53 healthy controls. Additionally, dual-energy X-ray absorptiometry was used to measure bone mineral density (BMD) at lumbar spine 1 to 4 and at...
Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation
Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease. The discovery points to a potential new treatment for the autoimmune disorder and may also allow the use of a simple blood test to detect people at...