by Massachusetts General Hospital Credit: CC0 Public Domain Researchers have published the results of a clinical trial that led the U.S. Food and Drug Administration to recently approve mitapivat for the treatment of adults with pyruvate kinase deficiency—a rare genetic condition that leads to the destruction of red blood cells, or hemolytic anemia. The primary...
The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a study led by researchers at Weill Cornell Medicine. The discovery could lead to new methods for classifying and treating patients with this disease. The researchers, who published their findings in Cell, found that in a...
Researchers at Harvard’s Wyss Institute have developed a way to deliver immune-stimulating agents to lung metastases. Their system involves nanoparticles loaded with an immune-stimulating agent that are attached to red blood cells. When injected into the blood stream, the red blood cells shed the nanoparticles as they squeeze through the narrow capillaries of the lungs, provoking...
