by University of Delaware NAD+ and NADH concentrations in NEVs and change–change correlations with insulin signaling proteins. (a) Concentration of NAD+ after 6 weeks of oral nicotinamide riboside (NR) supplementation was significantly higher in NEVs when compared to placebo (n = 10, p = 0.0092, paired ttest), while NADH remained relatively unchanged (n = 22, p = 0.215,...