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Researchers discover new lipid nanoparticle that shows muscle-specific mRNA delivery, reduces off-target effects.
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Researchers discover new lipid nanoparticle that shows muscle-specific mRNA delivery, reduces off-target effects.

by Kate Richards, University of Toronto—Leslie Dan Faculty of Pharmacy A team of researchers based at the University of Toronto’s (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle, iso-A11B5C1, that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues. Credit: Steve Southon, University of Toronto A...