by University of Virginia Doctors can examine COVID-19 patients’ blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator, new research from the University of Virginia School of Medicine suggests. The discovery could lead to new treatments to prevent deadly “cytokine storms” seen in severe...
Tag: <span>researchers</span>
Using Epo to treat COVID-19
by Max Planck Society Erythropoietin (Epo) is actually a medication for anemia. According to researchers at the Max Planck Institute of Experimental Medicine in Göttingen, the doping agent Epo could also be effective against COVID-19. The growth factor could mitigate severe disease progression and protect patients from long-term neurological effects when the SARS-CoV-2 virus attacks...
The protein that stands between us and autoimmunity
by Osaka University Tet-mediated B cell tolerance Tet2/3-deficient B cells are activated by self-antigen and express exaggerated amount of CD86. Then those B cells stimulate autoreactive CD4+ T cells, resulting in autoimmune response. Credit: Osaka University The immune system is supposed to protect from external microbial invaders, but sometimes it turns its efforts inward, potentially...
B-cell protectors
MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE IN THE HELMHOLTZ ASSOCIATION THE PROTEIN PDAP1 (RED) IS LOCATED IN THE CYTOPLASM OF B CELLS. view more CREDIT: DI VIRGILIO, MDC Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system’s most important...
Nuclear Softening Allows Cells to Move Into Dense Tissue, Encouraging Injury Repair
Using an enzyme inhibitor in meniscus cells, a Penn team was able to soften their nucleus and promote access to previously impassible areas. By softening a cell’s nucleus so that it can squeeze its way through dense connective tissues, a group of researchers believes they’ve demonstrated a new way to help the body efficiently repair...
A vaccine targeting aged cells mitigates metabolic disorders in obese mice
by Osaka University were defined as PD-1+ CD153+ cells in CD4+ T cells. The proportion of senescent T cells in visceral adipose tissues (VAT) of the high fat diet (HFD) control group was significantly increased compared with that in the VAT of the normal diet (ND) control group. CD153-CpG vaccination of HFD mice resulted in...
Researchers identify more than 100 toxic chemicals in cannabis smoke
by Michael Brown, University of Alberta University of Alberta engineering researchers have characterized the potentially hazardous particles in cannabis smoke and have raised awareness about their potential health effects. “It’s not out of line to say there’s potential health risk in marijuana smoke, and there’s not nearly enough research,” said Robert Nishida, a U of...
New approach for a biological programming language
by Graz University of Technology New findings by researchers led by TU Graz computer scientists Wolfgang Maass and Robert Legenstein on neural information processing in the brain could enable more efficient AI methods. Specifically, the researchers have succeeded in mathematically modeling the emergence and interaction between so-called “assemblies”. These are neuron groups in the brain...
Study reveals plant compound beats sugar cravings
by Massey University With millions of people around the world still confined to their homes due to COVID-19 lockdown restrictions, many have reported over-indulging in home-baking, snacks and sugary treats, potentially leading to increases in body weight. But researchers at Massey University may have found a solution by investigating a plant compound that showed a...
New findings redefine organisation of the claustrum
Researchers from Karolinska Institutet and Nanyang Technological University (NTU) in Singapore have found that the claustrum is organized into functional connectivity modules rather than a hub-like structure, which up until now, was the prevailing idea. The study was recently published in Current Biology. “We found that the synaptic connectivity between the cortex and claustrum is...