Scientists were able to prevent obesity in mice by blocking macrohages, key inflammatory cells, within the body. Researchers from the Washington University School of Medicine in St. Louis have successfully disabled a gene in specific mouse cells, preventing mice from becoming obese even after being fed a high-fat diet. Macrophages, vital inflammatory cells which are...
by National Research Council of Science & Technology Bang Eun-kyoung(left) from the KIST’s Center for Neuro-Medicine are discussing the efficacy of RNA stabilizer containing zinc complex. Credit: Korea Institute of Science and Technology (KIST) MERS, which struck South Korea in a 2015 outbreak, was caused by a coronavirus, the same family of viruses that is...
by Karolinska Institutet In severe cases of COVID-19, a massive release of the endogenous protein HMGB1 in the lungs may contribute to pulmonary inflammation and tissue damage, according to a review article published today in the scientific journal Molecular Medicine. The researchers conclude that the inflammation could hypothetically be treated with an HMGB1 inhibitor. Severe...
by Bob Yirka , Medical Xpress RUVBL2 protein (in red) acts to integrate the circadian repressive super-complex, and how the physiological metabolite of cordycepin (CoTP, the green key) breaks down the complex and causes a 12-hour clock phase-shift. Credit: Zhancong Xu A team of researchers from several institutions in China and two in the U.S....
CINCINNATI – After 20 years of trying, modern medicine remains unable to lower the roughly 40 percent mortality rate for the severe childhood immune disease called HLH (hemophagocytic lymphohistiocytosis), which damages vital organs and tissues. Now, researchers report in the New England Journal of Medicine treating patients with a new drug that saved kid’s lives...
People with the mental health condition known as body integrity dysphoria (BID) often feel as though one of their healthy limbs isn’t meant to be a part of their bodies. They may act as though the limb is missing or even seek its amputation “to feel complete.” Now, researchers reporting in the journal Current Biology...
by University of Barcelona\ Researchers from the Faculty of Medicine of the University of Barcelona and the CELLEX Biomedical Research Centre from IDIBAPS, in collaboration with scientists from the University of Sydney, University of London and the Research Institute Sant Joan de Déu, have identified in a study with mice a protein which is fundamental...
by Karolinska Institutet According to many observations, certain virus infections may play a part in the autoimmune attack that leads to type 1 diabetes. Researchers at Karolinska Institutet in Sweden and their Finnish colleagues have now produced a vaccine for these viruses in the hope that it could provide protection against the disease. The study...
May 4, 2020 — A study at Columbia University Mailman School of Public Health found that long-term buprenorphine treatment is associated with improvements in health care outcomes. Compared to individuals who discontinued buprenorphine, those with continuous treatment had significantly lower rates of prescription opioid use and opioid-related events, including medically treated overdoses in the follow-up...
by Amanda Morris, Northwestern University The more we learn about the novel coronavirus (COVID-19), the more unknowns seem to arise. These ever-emerging mysteries highlight the desperate need for more data to help researchers and physicians better understand—and treat—the extremely contagious and deadly disease. Researchers at Northwestern University and Shirley Ryan AbilityLab in Chicago have developed...
