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Researchers unravel protein mystery of three brain diseases

by KU Leuven Microscopic image of mouse neurons to which the patient-derived α-synuclein protein was administered. The protein deposits (green) form after seven days. Credit: Microscopy by Anke Van der Perren The accumulation of one particular protein in the brain is the basis of three very different age-related conditions. Until recently, nobody understood how this...

Low vitamin D, smoking predict worse cognitive function in MS
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Low vitamin D, smoking predict worse cognitive function in MS

(HealthDay)—For multiple sclerosis (MS) patients with clinically isolated syndrome, lower vitamin D and smoking predict worse long-term cognitive function and neuronal integrity, according to a study published online April 16 in Neurology. Marianna Cortese, M.D., Ph.D., from the University of Bergen in Norway, and colleagues conducted a study involving 278 patients with clinically isolated syndrome...

Researchers are developing potential treatment for chronic pain
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Researchers are developing potential treatment for chronic pain

Researchers from the University of Copenhagen have developed a new way to treat chronic pain which has been tested in mice. With a compound designed and developed by the researchers themselves, they can achieve complete pain relief. Between seven and ten percent of the world’s population suffers from chronic pain originating from nerves that have...

Nanostimulators boost stem cells for muscle repair
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Nanostimulators boost stem cells for muscle repair

CHAMPAIGN, Ill. — In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells. In a new study published in the journal ACS Nano, researchers at the University of Illinois at Urbana-Champaign demonstrated that “nanostimulators” – nanoparticles...

Researchers identify unique glucose-sensing neurons that regulate blood sugar
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Researchers identify unique glucose-sensing neurons that regulate blood sugar

by Baylor College of Medicine Low blood sugar levels, known as hypoglycemia, can be a life-threatening situation, especially for people with type 1 diabetes who rely on intensive insulin therapy to prevent blood sugar from going too high. Solutions to this problem may come from a better understanding of the basic mechanisms keeping blood sugar...

New Brain-Computer Interface Restores Movement and Sense of Touch to Paralysed Limbs with 90% Accuracy
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New Brain-Computer Interface Restores Movement and Sense of Touch to Paralysed Limbs with 90% Accuracy

A group of researchers from the Battelle Memorial Institute (BMI) in Columbus, Ohio has developed a new brain-computer interface which restores both movement and sense of touch to the limbs of patients with spinal cord injuries (SCIs). Even though such technology has already been tested in the past, what makes the new system remarkable is...

UTEP researchers develop nanohybrid vehicle to optimally deliver drugs into the human body
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UTEP researchers develop nanohybrid vehicle to optimally deliver drugs into the human body

BY: MAHESH NARAYAN. EL PASO, Texas – Researchers in The University of Texas at El Paso’s Department of Chemistry and Biochemistry have developed a nanohybrid vehicle that can be used to optimally deliver drugs into the human body. The research was published in April 2020 in ACS Applied Materials & Interfaces. Leading the study are...

Clascoterone cream safe, effective for acne treatment
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Clascoterone cream safe, effective for acne treatment

Adelaide Hebert, M.D., from the University of Texas Health Science Center in Houston, and colleagues assessed the safety and efficacy of clascoterone cream, 1 percent, a novel topical androgen receptor inhibitor, in two phase 3 clinical trials (including a total 1,440 patients) in which patients were randomly assigned to clascoterone cream, 1 percent, or a...

Higher manganese intake may be tied to lower type 2 diabetes risk
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Higher manganese intake may be tied to lower type 2 diabetes risk

Jung Ho Gong, from Brown University in Providence, Rhode Island, and colleagues evaluated the association between manganese intake and the risk for type 2 diabetes in 84,285 postmenopausal women without a history of diabetes participating in the national Women’s Health Initiative Observational Study (WHI-OS). Results were validated in the 62,338 women who participated in the...