Peer-Reviewed Publication UNIVERSITY OF COLOGNE CREDIT: CSSB/BIAO YUAN CRYO-ELECTRON MICROSCOPE RECONSTRUCTION OF THE BINDING OF A HUMAN ANTI-PCRV FAB ANTIBODY (YELLOW) TO A PCRV PENTAMER (BLUE) OF THE TYPE III SECRETION SYSTEM (T3SS) OF PSEUDOMONAS AERUGINOSA. THE ANTIBODY BINDING LEADS TO AN INHIBITION OF THE T3SS, WHICH IS AN IMPORTANT VIRULENCE FACTOR OF P. AERUGINOSA....
by NanJing Agricultural University Examples of the combination of nanotechnology with phages. (A) Use of phages conjugated with gold NPs for the identification of bacteria (detection, sensing, typing) based on color changes due to their surface plasmon resonance properties. (B) Use of phages conjugated with gold nanorods (AuNRs) for focalized photothermal therapy. (C) Encapsulation and adsorption...
UNIVERSITY OF SOUTHERN DENMARK IMAGE: LAB WORK AT UNIVERSITY OF SOUTHERN DENMARK CREDIT: EMIL RYGE/UNIVERSITY OF SOUTHERN DENMARK Antibiotic resistance is a ticking bomb under public health. WHO predicts that in 2050 more people will die from infections than from cancer – and we are talking about infections that we today consider harmless; infections that...
by University of Illinois at Chicago Structural visualizations reveal that iboxamycin displaces the methylated nucleotide and binds in deep pocket of the ribosome. Credit: Polikanov, et al. A new study published in Nature reports on a new antibiotic that binds to the ribosome of bacterial cells and stops drug-resistant pathogens from making mice sick. Co-authored by researchers...
Growing resistance to our go-to antibiotics is one of the biggest threats the world faces. As common bacteria like strep and salmonella become resistant to medications, what used to be easily treatable infections can now pose difficult medical challenges. New research from the University of Georgia shows that there may be more antimicrobial-resistant salmonella in our food...
AMERICAN SOCIETY FOR MICROBIOLOGY Washington, DC – June 20, 2021 – Researchers from the Miami University in Ohio have optimized a new technique that will allow scientists to evaluate how potential inhibitors work on antibiotic-resistant bacteria. This technique, called native state mass spectrometry, provides a quick way for scientists to identify the best candidates for effective clinical...
CHALMERS UNIVERSITY OF TECHNOLOGY IMAGE: Researchers at Chalmers University of Technology, Sweden, have developed a new material that kills bacteria and could potentially prevent infections in wounds – a specially designed hydrogel, that works against all types of bacteria, including antibiotic-resistant ones. The active substance in the new bactericidal material consists of antimicrobial peptides, small...
by Birgitte Svennevig, University of Southern Denmark A colorized scanning electron micrograph of MRSA. Credit: National Institute of Allergy and Infectious Diseases Every day, people die from simple infections even though they have been treated with antibiotics. This is because more and more bacteria have become resistant to the types of antibiotics that doctors can prescribe....
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Antibiotic resistance is one of the world’s most urgent public health threats. In the United States alone, tens of thousands of deaths result each year from drug-resistant strains of common bacteria such as Staphylococcus aureus and Enterococcus faecium, which can cause virtually untreatable hospital-acquired infections. Perilously few new classes...
by University of Gothenburg A hitherto unknown antibiotic-resistant bacteria species, in the same family as E. coli and Salmonella spp., has been found and classified in Sweden. The proposed taxonomic name of the species—the first of the new genus—is Scandinavium goeteborgense, after the city of Gothenburg, where the bacterium was isolated and the research was...
