Highlights hPSC-derived photoreceptors express markers in a pattern similar to human development 2D/3D differentiation protocol generates sufficient cones for transplantation hPSC-derived cones incorporate into the adult retina following transplantation Summary Transplantation of rod photoreceptors, derived either from neonatal retinae or pluripotent stem cells (PSCs), can restore rod-mediated visual function in murine models of inherited blindness....