by Tohoku University Neurodegenerative diseases such as Alzheimer’s disease and dementia with Lewy body (DLB) are caused by the accumulation of aggregated amyloid-beta and α-synuclein, respectively. The aggregated proteins impaired the proteasome activity, thereby exacerbating neuronal death. On the other hand, we developed a novel T-type calcium channel enhancer SAK3 in 2017. Since the T-type calcium...
