by Mass General Brigham Credit: Karolina Grabowska from PexelsRheumatoid arthritis impacts approximately 2 million people in the United States and is associated with increased risk of cardiovascular disease. However, assessing cardiovascular risk is difficult in patients with rheumatoid arthritis because standard clinical assessments based on factors like age, cholesterol, and smoking status tend to underestimate cardiovascular...
by FAPESP 1: Summary of the experimental sessions. The exercise (upper panel) and control sessions (lower panel) were performed in different days and the order of the experiments was randomized. Both sessions were composed by pre- and post-interventions of blood pressure (BP) and heart rate (HR) at rest and in response to the Stroop Color and...
Randy Dotinga November 20, 2023 SAN DIEGO – Researchers say they’ve developed a novel blood-based assay that can differentiate patients with seropositive or seronegative rheumatoid arthritis from healthy people and those with other inflammatory diseases or osteoarthritis. While cautioning that the results need to be confirmed, University of Oxford (England) rheumatologist Peter Taylor, PhD, MA,...
by American College of Rheumatology Credit: Pixabay/CC0 Public Domain New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, shows that treating rheumatoid arthritis with hydroxychloroquine (HCQ) reduced the risk of nonalcoholic fatty liver disease, especially in women and men who are 50 years old and younger. Rheumatoid arthritis (RA) is a...
Ceria nano particle-immobilized mesenchymal stem cell nanovesicle hybrid system offers both immediate pain relief and long-term immune tolerance Peer-Reviewed Publication INSTITUTE FOR BASIC SCIENCE SCHEMATIC ILLUSTRATION OF COMPREHENSIVE AND COMBINATION RA THERAPY BY CE-MSCNV NANOPARTICLES. CE-MSCNVS SCAVENGE THE OVER-PRODUCED ROS IN AN RA KNEE JOINT, INDUCE M1 TO M2 MACROPHAGE POLARIZATION FOR IMMEDIATE RELIEF OF...
by Merve Ozen, University of Kentucky Credit: Pixabay/CC0 Public DomainOf all the joints in the body, the knees get the most wear and tear. Decades of walking, running, sitting, jumping and other activities can take a toll on the cartilage—the smooth tissue between the bones—leading to osteoarthritis. The resulting pain and stiffness can limit mobility...
by University of Birmingham Credit: Pixabay/CC0 Public Domain Researchers have shown that a novel antibody generated to target an ‘essential amino acid sequence’ of both interleukin-17A and F has greater activity and potentially fewer side effects than existing biological therapies for conditions such as as rheumatoid arthritis (RA), psoriasis, and inflammatory bowel disease (IBD). The antibody, called...
by Lori Solomon Rheumatoid arthritis (RA) is associated with a higher risk for developing aortic stenosis, according to a study published online July 31 in JAMA Internal Medicine. Tate M. Johnson, M.D., from the VA Nebraska-Western Iowa Health Care System in Omaha, and colleagues examined the risk for incident aortic stenosis, aortic valve intervention, aortic stenosis-related death,...
by Elana Gotkine Peresolimab, a humanized immunoglobulin G1 monoclonal antibody designed to stimulate the endogenous programmed cell death protein 1 (PD-1) inhibitory pathway, is efficacious for patients with rheumatoid arthritis, according to a study published in the May 18 issue of the New England Journal of Medicine. Jay Tuttle, Ph.D., from Eli Lilly in San Diego,...
by Justin Jackson, Medical Xpress Credit: Unsplash/CC0 Public Domain Research led by Kosin University College of Medicine in Korea has found a correlation between patients with rheumatoid arthritis and Parkinson’s disease. In their paper published in JAMA Neurology, researchers found a significantly higher risk of Parkinson’s disease (PD) in patients with rheumatoid arthritis (RA). In a cohort study of...
