Rheumatoid arthritis can cause inflammation and pain in the joints, including the spine and hips. This can cause back pain and stiffness. Rheumatoid arthritis (RA) can cause inflammation in any joint. For some people, RA affects the joints in the spine, causing stiffness and pain. RA may also be related to sciatica. There are some home and medical treatments...
Tag: <span>rheumatoid arthritis</span>
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Gum disease may be a key initiator of rheumatoid arthritis related autoimmunity
The results of a study presented at the Annual European Congress of Rheumatology (EULAR 2018) demonstrates increased levels of gum disease, and disease-causing bacteria, in individuals at risk of rheumatoid arthritis (RA). “It has been shown that RA-associated antibodies, such as anti-citrullinated protein antibodies, are present well before any evidence of joint disease. This suggests...
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Discovery of novel biomarker with remarkable specificity to rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disorder that occurs when the immune system mistakenly attacks the body’s tissues. Unlike the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the lining of the joints, causing painful swelling that can eventually result in bone erosion and joint deformity. Most RA patients are positive for anticitrullinated protein antibodies (ACPA), and these antibodies are...
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Drug compound shows promise against rheumatoid arthritis
Scientists have designed a new drug compound that dials down inflammation, suggesting possible future uses against autoimmune disorders such as rheumatoid arthritis. The new inhibitor is more selective than other compounds designed to target the same inflammatory pathway, according to new research from Washington University School of Medicine in St. Louis. Such precision, along with...
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Chromosomal loop signatures could identify poor drug response in arthritis
Chromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequately to ‘anchor’ treatment drug methotrexate. New University of Glasgow research, published in the Journal of Translational Medicine, investigated whether differences in genomic architecture, as defined by a chromosome conformation signature (CCS) in blood taken pre-treatment from...
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Gold injections: Can they treat rheumatoid arthritis?
Gold treatments were one of the earliest treatments for rheumatoid arthritis going back at least 75 years. There is no cure for rheumatoid arthritis (RA). Medications can slow down the disease, while complementary therapies can help people cope with the joint pain and stiffness, chronic fatigue, and other symptoms, such as low-grade fevers and dry skin and eyes. While gold...
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New oral treatment option for rheumatoid arthritis
Patients suffering from rheumatoid arthritis are treated for around six months with the standard anti-rheumatic agent methotrexate, to which many patients respond very well. However, if they do not respond and no remission or at least reduction in the activity of the disease can be achieved, they are given a combined treatment of methotrexate and...
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Discovery of new T-cell subtype opens window on rheumatoid arthritis
Finding flows from researchers’ use of high-tech tools to deeply and efficiently characterize patient cells Rheumatoid arthritis is an autoimmune condition in which the immune system attacks the joints, causing inflammation, pain, and eventually destruction of the tissues that make up this essential body part. A research team led by scientists from Brigham and Women’s...
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Rheumatoid arthritis: New treatment option for difficult-to-treat patients
Between 3 and 5% of the population suffer from a form of inflammatory rheumatism. It affects approximately 250,000 — 400,000 people in Austria. Rheumatoid arthritis is one of the commonest and also the most dangerous forms of this inflammatory rheumatic disease. Around 30% of patients achieve remission, that is to say successful control of symptoms,...
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Pitt study provides clues to relationship between schizophrenia and rheumatoid arthritis
PITTSBURGH, Feb. 24, 2017 – An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at lower risk for the other, according to the results of a...