by American College of Rheumatology Credit: Pixabay/CC0 Public Domain New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, shows that treating rheumatoid arthritis with hydroxychloroquine (HCQ) reduced the risk of nonalcoholic fatty liver disease, especially in women and men who are 50 years old and younger. Rheumatoid arthritis (RA) is a...
Ceria nano particle-immobilized mesenchymal stem cell nanovesicle hybrid system offers both immediate pain relief and long-term immune tolerance Peer-Reviewed Publication INSTITUTE FOR BASIC SCIENCE SCHEMATIC ILLUSTRATION OF COMPREHENSIVE AND COMBINATION RA THERAPY BY CE-MSCNV NANOPARTICLES. CE-MSCNVS SCAVENGE THE OVER-PRODUCED ROS IN AN RA KNEE JOINT, INDUCE M1 TO M2 MACROPHAGE POLARIZATION FOR IMMEDIATE RELIEF OF...
by Merve Ozen, University of Kentucky Credit: Pixabay/CC0 Public DomainOf all the joints in the body, the knees get the most wear and tear. Decades of walking, running, sitting, jumping and other activities can take a toll on the cartilage—the smooth tissue between the bones—leading to osteoarthritis. The resulting pain and stiffness can limit mobility...
by University of Birmingham Credit: Pixabay/CC0 Public Domain Researchers have shown that a novel antibody generated to target an ‘essential amino acid sequence’ of both interleukin-17A and F has greater activity and potentially fewer side effects than existing biological therapies for conditions such as as rheumatoid arthritis (RA), psoriasis, and inflammatory bowel disease (IBD). The antibody, called...
by Lori Solomon Rheumatoid arthritis (RA) is associated with a higher risk for developing aortic stenosis, according to a study published online July 31 in JAMA Internal Medicine. Tate M. Johnson, M.D., from the VA Nebraska-Western Iowa Health Care System in Omaha, and colleagues examined the risk for incident aortic stenosis, aortic valve intervention, aortic stenosis-related death,...
by Elana Gotkine Peresolimab, a humanized immunoglobulin G1 monoclonal antibody designed to stimulate the endogenous programmed cell death protein 1 (PD-1) inhibitory pathway, is efficacious for patients with rheumatoid arthritis, according to a study published in the May 18 issue of the New England Journal of Medicine. Jay Tuttle, Ph.D., from Eli Lilly in San Diego,...
by Justin Jackson, Medical Xpress Credit: Unsplash/CC0 Public Domain Research led by Kosin University College of Medicine in Korea has found a correlation between patients with rheumatoid arthritis and Parkinson’s disease. In their paper published in JAMA Neurology, researchers found a significantly higher risk of Parkinson’s disease (PD) in patients with rheumatoid arthritis (RA). In a cohort study of...
By Paul McClure May 11, 2023 When a person with rheumatoid arthritis receives healthy antibodies, it can reduce inflammation and bone degeneration. Researchers have, for the first time, discovered the molecular pathways that underlie this process Depositphotos Injecting antibodies from a healthy person into someone suffering from rheumatoid arthritis can reduce inflammation and slow bone...
The presence of anti-CCP in a person’s blood may indicate they have rheumatoid arthritis (RA). When the immune system produces anti-CCP, it triggers a series of reactions that damage tissues in the joints. This can result in pain, stiffness, and swelling. Anti-CCP is an auto-antibody. This is a protein the immune system can make that...
by Osaka University We all know that a strong immune system is a definite advantage. Yet, sometimes, the immune system goes awry and attacks the body. This autoimmunity is the cause of various disorders, such as rheumatoid arthritis, Crohn’s disease, type 1 diabetes, and celiac disease. To fight these diseases, it is crucial to determine...
