(HealthDay)—Magnetic resonance imaging (MRI) of the hand and foot may predict rheumatoid arthritis (RA) in patients presenting with undifferentiated arthritis (UA), according to a study published online Jan. 12 in Rheumatology. Nikolet K. den Hollander, M.D., Ph.D., from the Leiden University Medical Center in the Netherlands, and colleagues studied the predictive value of MRI for progression...
by Washington State University Credit: Unsplash/CC0 Public Domain Cells from a cheek swab revealed biomarkers for rheumatoid arthritis that could lead to a way to diagnose and begin treatment before the disease develops, according to a study published in Scientific Reports. In the study, researchers from Washington State University and Arthritis Northwest in Spokane, Washington identified...
by Sara Tiner, Mayo Clinic Credit: Unsplash/CC0 Public Domain Mayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new Nature Immunology publication. In “helper” T cells from patients with rheumatoid arthritis, low levels of a specific amino acid lead to cellular miscommunication, but supplying it may provide...
By Rich Haridy November 09, 2021 A large trial is currently underway in the United States testing an implant (pictured above) that is hoped to treat rheumatoid arthritis by delivering short bursts of electrical stimulation to the vagus nerve Could the future of rheumatoid arthritis treatment be a small implant designed to deliver bursts of...
by American College of Rheumatology Credit: CC0 Public Domain New research presented this week at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that in one study, the majority of rheumatoid arthritis patients on an ultra-low dose of the drug rituximab maintained low disease activity for up to four years, and rarely needed...
UW Medicine physicians are helping conduct a study to see whether nerve stimulation can reduce the inflammation that causes rheumatoid arthritis. This is the first large-scale trial to see if manipulating the nervous system can influence the immune system. The study reflects a growing interest in the use of electrical devices — so-called electroceuticals —...
Rheumatoid arthritis (RA) is an autoimmune condition, meaning the immune system mistakenly attacks healthy tissues. RA in the knees may severely affect a person’s mobility. RA commonly affects the joints in the hands, wrists, and knees, causing the lining of the joints to become inflamed and damaged. RA is typically symmetrical, affecting both sides of...
UNIVERSITY OF TOLEDO IMAGE: DR. RITU CHAKRAVARTI, ASSISTANT PROFESSOR IN THE UNIVERSITY OF TOLEDO COLLEGE OF MEDICINE AND LIFE SCIENCES, IS THE LEAD AUTHOR OF A NEW PAPER PUBLISHED IN THE PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES DETAILING THE CREATION OF AN EXPERIMENTAL VACCINE AGAINST RHEUMATOID ARTHRITIS. CREDIT: DANIEL MILLER | THE UNIVERSITY OF...
by Katherine Unger Baillie, University of Pennsylvania Graphical abstract. Credit: DOI: 10.1172/JCI150578 Rheumatoid arthritis (RA) is an autoimmune, inflammatory disease. Though the precise mechanism of the disease is only partially understood, people with RA produce antibodies that target their own tissues, contributing to painful inflammation in the joints that can cause bone loss. In a new...
by Josh Barney, University of Virginia Fig. 1: Elmo1−/− mice have reduced bone erosion in two models of osteoporosis. a Single-nucleotide polymorphisms (SNP)-disease and phenotype associations discovered via search of the GWASdb SNP-Disease and six other SNP-phenotype association databases. The data are plotted using a standardized p value. Databases used and specific SNPs are indicated in Supplementary...
