by Queen Mary, University of London Human heart. Credit: copyright American Heart Association Researchers from Queen Mary University of London have developed a new approach to address cardiac disease in rheumatoid arthritis (RA) patients. Currently patients with RA are particularly susceptible to a type of cardiac deficiency termed diastolic dysfunction, which may lead to heart failure, resulting in...
by University College London Section of graphical abstract from paper. Credit: Med UCL researchers have shown that damage to the lining of the gut plays an important role in the development of rheumatoid arthritis, paving the way for a new approach to treating the disease. In the pre-clinical study, which used mouse models and patient samples, the research team propose...
by Washington University School of Medicine Researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, deliver a biologic drug in response to inflammation. Pictured is an implant consisting of a woven scaffold coated with the engineered cartilage cells that release a drug in response to...
by Brigham and Women’s Hospital Credit: CC0 Public Domain A new study by investigators from Brigham and Women’s Hospital found a potential direct link between exposure to parental smoking during childhood and increased risk of seropositive rheumatoid arthritis (RA) later in life. Researchers utilized established longitudinal data from 90,923 women in the Nurses’ Health Study II...
Investigators found similarities in the bacterial composition of the mouth among patients with early rheumatoid arthritis and those at risk of developing the disease, compared with healthy individuals who were not at risk. The findings come from a study published in Arthritis & Rheumatology. Image credit: arembowski via Pixabay, free license Patients and at-risk individuals...
Rheumatoid arthritis (RA) is an autoimmune condition that causes inflammation of the joints and can affect the neck. According to a 2018 literature review, a person will rarely experience RA symptoms in the neck in the early stages of the condition. In this article, we look at how RA affects the neck. We also discuss the...
Eleven novel loci and 90 independent association signals have been identified for rheumatoid arthritis (RA), according to a study published in the May issue of the Annals of the Rheumatic Diseases. Eunji Ha, from Kyung Hee University in Seoul, South Korea, and colleagues conducted a meta-analysis of genome-wide RA association summary statistics in three large case-control...
by Monash University Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis (RA). Credit: Erica Tandori Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes...
by Judith Van Dongen, Washington State University Study authors Mahamudul Haque, Salah-Uddin Ahmed, and Anil K. Singh look at a protein array in their lab at the WSU Health Sciences Spokane campus. Credit: Cori Kogan, Washington State University Health Sciences Spokane New research led by scientists at Washington State University has found that a protein known as GBP5 appears...
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO IMAGE: SCIENTISTS IDENTIFIED A NOVEL PATHWAY IN THE INFLAMMATORY PROCESS RELATING TO BONE DAMAGE. CREDIT: PAULA DONATE In a study aimed at investigating the mechanism responsible for exacerbating rheumatoid arthritis in smokers, researchers at the Center for Research on Inflammatory Diseases (CRID), linked to the...
